About the Authors

Benjamin F. Voight, Cameron D. Palmer, Noël P. Burtt, Richa Saxena, Elizabeth K. Speliotes, Jared Maguire, Melissa Parkin, Wendy Winckler, Sekar Kathiresan, Christopher Newton-Cheh, Joel N. Hirschhorn, David Altshuler
Medical Population Genetics, The Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Benjamin F. Voight
Department of Pharmacology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America

Hyun Min Kang, Carlo Sidore, Christian Fuchsberger, Yanming Li, Anne U. Jackson, Tanya M. Teslovich, Gonçalo R. Abecasis, Michael Boehnke
Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America

Jun Ding, Ramaiah Nagaraja
Laboratory of Genetics, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America

Cameron D. Palmer, Joel N. Hirschhorn
Divisions of Endocrinology and Genetics and Program in Genomics, Children's Hospital, Boston, Massachusetts, United States of America

Carlo Sidore, Serena Sanna, Antonella Mulas, Francesco Cucca
Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche (CNR), Monserrato, Italy

Carlo Sidore, Francesco Cucca
Dipartimento di Scienze Biomediche, Università di Sassari, Sassari, Italy

Peter S. Chines
Genome Technology Branch, National Human Genome Research Institute, Bethesda, Maryland, United States of America

Jeanette Erdmann, Heribert Schunkert
Universität zu Lübeck, Medizinische Klinik II, and Nordic Center of Cardiovascular Research, Lübeck, Germany

Timothy M. Frayling
Genetics of Complex Traits, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom

Iris M. Heid
Department of Epidemiology and Preventive Medicine, University Hospital Regensburg, Regensburg, Germany

Iris M. Heid
Helmholtz Zentrum München—German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany

Toby Johnson, Patricia B. Munroe
Clinical Pharmacology and Barts and the London Genome Centre, William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, United Kingdom

Tuomas O. Kilpeläinen, Ruth J. F. Loos
MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom

Cecilia M. Lindgren, Andrew P. Morris, Inga Prokopenko, Joshua C. Randall, N. William Rayner, Neil Robertson, Mark I. McCarthy
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

Inga Prokopenko, N. William Rayner, Neil Robertson, Mark I. McCarthy
Oxford Centre for Diabetes, Endocrinology, and Metabolism, Churchill Hospital, University of Oxford, Oxford, United Kingdom

Richa Saxena, Sekar Kathiresan, Christopher Newton-Cheh, David Altshuler
Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Richa Saxena
Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Nicole Soranzo, Eleanor Wheeler, Simon Potter, N. William Rayner, Kathleen Stirrups, Inês Barroso, Panos Deloukas
Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom

Elizabeth K. Speliotes
Department of Internal Medicine, Division of Gastroenterology and Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, United States of America

Inês Barroso
University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom

Sekar Kathiresan, Christopher Newton-Cheh
Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Sekar Kathiresan, Christopher Newton-Cheh, David Altshuler
Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America

Arne Pfeufer
Institute of Human Genetics, Klinikum Rechts der Isar Technische Universität München, Munich, Germany

Arne Pfeufer
Institute of Human Genetics, Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt, Neuherberg, Germany

Arne Pfeufer
EURAC Center of Biomedicine, Bolzano, Italy

Nilesh J. Samani
Department of Cardiovascular Sciences, Glenfield Hospital, University of Leicester, Leicester, United Kingdom

Nilesh J. Samani
Leicester NIHR Biomedical Research Unit in Coronary Artery Disease, Glenfield Hospital, Leicester, United Kingdom

Joel N. Hirschhorn, David Altshuler
Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

David Altshuler
Department of Molecular Biology, Harvard Medical School, Boston, Massachusetts, United States of America

David Altshuler
Diabetes Unit, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Mark I. McCarthy
Oxford NIHR Biomedical Research Centre, Churchill Hospital, Oxford, United Kingdom

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BFV HMK JNH DA MIM GRA MB. Analyzed the data: BFV HMK JD CDP CS PSC NPB CF YL JE TMF IMH AUJ TJ TOK CML APM IP JCR RS NS EKS TMT EW JM MP SP NWR NR KS WW SS AM. Contributed reagents/materials/analysis tools: AM RN FC IB PD RJFL SK PBM CN-C AP NJS HS. Wrote the paper: BFV HMK GRA MB. Critically revised the manuscript, including comments and feedback: BFV HMK JE TMF TOK CML NS NWR SS RN IB RJFL SK CN-C NJS JNH DA MIM GRA MB.