About the Authors
- Altuna Akalin
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Contributed equally to this work with: Altuna Akalin, Francine E. Garrett-Bakelman
Affiliation Department of Physiology and Biophysics and the HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medical College, New York, New York, United States of America
- Francine E. Garrett-Bakelman
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Contributed equally to this work with: Altuna Akalin, Francine E. Garrett-Bakelman
Affiliation Department of Medicine, Division of Hematology/Oncology, Weill Cornell Medical College, New York, New York, United States of America
- Matthias Kormaksson
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Affiliation Department of Public Health, Weill Cornell Medical College, New York, New York, United States of America
- Jennifer Busuttil
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Affiliation Department of Medicine, Division of Hematology/Oncology, Weill Cornell Medical College, New York, New York, United States of America
- Lu Zhang
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Affiliation Illumina, Hayward, California, United States of America
- Irina Khrebtukova
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Affiliation Illumina, Hayward, California, United States of America
- Thomas A. Milne
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Affiliation MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom
- Yongsheng Huang
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Affiliation Department of Pathology, University of Michigan, Ann Arbor, Michigan, United States of America
- Debabrata Biswas
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Affiliation Laboratory of Chromatin Biology, The Rockefeller University, New York, New York, United States of America
- Jay L. Hess
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Affiliation Department of Pathology, University of Michigan, Ann Arbor, Michigan, United States of America
- C. David Allis
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Affiliation Laboratory of Chromatin Biology, The Rockefeller University, New York, New York, United States of America
- Robert G. Roeder
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Affiliation Laboratory of Molecular Biology and Biochemistry, The Rockefeller University, New York, New York, United States of America
- Peter J. M. Valk
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Affiliation Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands
- Bob Löwenberg
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Affiliation Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands
- Ruud Delwel
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Affiliation Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands
- Hugo F. Fernandez
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Affiliation Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America
- Elisabeth Paietta
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Affiliation Cancer Center, Montefiore Medical Center–North Division, Bronx, New York, United States of America
- Martin S. Tallman
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Affiliation Leukemia Service, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America
- Gary P. Schroth
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Affiliation Illumina, Hayward, California, United States of America
- Christopher E. Mason
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* E-mail: chm2042@med.cornell.edu (CEM); amm2014@med.cornell.edu (AM); marfigue@med.umich.edu (MEF)
Affiliation Department of Physiology and Biophysics and the HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medical College, New York, New York, United States of America
- Ari Melnick
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* E-mail: chm2042@med.cornell.edu (CEM); amm2014@med.cornell.edu (AM); marfigue@med.umich.edu (MEF)
Affiliations Department of Medicine, Division of Hematology/Oncology, Weill Cornell Medical College, New York, New York, United States of America, Department of Pharmacology, Weill Cornell Medical College, New York, New York, United States of America
- Maria E. Figueroa
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* E-mail: chm2042@med.cornell.edu (CEM); amm2014@med.cornell.edu (AM); marfigue@med.umich.edu (MEF)
Affiliation Department of Pathology, University of Michigan, Ann Arbor, Michigan, United States of America
Competing Interests
GPS, IK, LZ, and JB are currently or have until recently been employed by Illumina.
Author Contributions
Conceived and designed the experiments: MEF AM. Performed the experiments: FEG-B JB MEF. Analyzed the data: AA MK FEG-B MEF CEM AM. Contributed reagents/materials/analysis tools: AA MK GPS PJMV BL RD EP MST IK LZ HFF. Wrote the paper: FEG-B AA MK CEM AM MEF. Contributed MLL ChIP-seq experiments: TAM DB CDA RGR. Contributed HOXA9 and MEIS1 ChIP-seq experiments: YH JLH. Critically reviewed the final manuscript prior to submission: all authors.