About the Authors

Mitsuhiro Endoh

mendoh@rcai.riken.jp (ME); koseki@rcai.riken.jp (HK)

Affiliations Laboratory for Developmental Genetics, RIKEN Research Center for Allergy and Immunology, Yokohama, Japan, Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Yokohama, Japan

Takaho A. Endo

Contributed equally to this work with: Takaho A. Endo, Tamie Endoh

Affiliation RIKEN Bioinformatics and System Engineering Division, Yokohama, Japan

Tamie Endoh

Contributed equally to this work with: Takaho A. Endo, Tamie Endoh

Affiliation Laboratory for Developmental Genetics, RIKEN Research Center for Allergy and Immunology, Yokohama, Japan

Kyo-ichi Isono

Affiliation Laboratory for Developmental Genetics, RIKEN Research Center for Allergy and Immunology, Yokohama, Japan

Jafar Sharif

Affiliation Laboratory for Developmental Genetics, RIKEN Research Center for Allergy and Immunology, Yokohama, Japan

Osamu Ohara

Affiliation Laboratories for Immunogenomics, RIKEN Research Center for Allergy and Immunology, Yokohama, Japan

Tetsuro Toyoda

Affiliation RIKEN Bioinformatics and System Engineering Division, Yokohama, Japan

Takashi Ito

Affiliation Department of Biochemistry, Nagasaki University School of Medicine, Nagasaki, Japan

Ragnhild Eskeland

Affiliation MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom

Wendy A. Bickmore

Affiliation MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom

Miguel Vidal

Affiliations Cell Proliferation and Development, Centro de Investigaciones Biologicas, Consejo Superior de Investigaciones Científicas, Madrid, Spain, Research Unit for Immunoepigenetics, RIKEN Research Center for Allergy and Immunology, Yokohama, Japan

Bradley E. Bernstein

Affiliations Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America

Haruhiko Koseki

mendoh@rcai.riken.jp (ME); koseki@rcai.riken.jp (HK)

Affiliations Laboratory for Developmental Genetics, RIKEN Research Center for Allergy and Immunology, Yokohama, Japan, Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Yokohama, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ME HK. Performed the experiments: ME TE K-iI. Analyzed the data: TAE OO TT. Contributed reagents/materials/analysis tools: TI RE WAB MV. Wrote the paper: ME JS WAB BEB HK.