About the Authors

John R. B. Perry, Andrew T. Hattersley, Michael N. Weedon, Timothy M. Frayling
Genetics of Complex Traits, Peninsula Medical School, University of Exeter, Exeter, United Kingdom

John R. B. Perry, Andrew P. Morris, Inga Prokopenko, William Rayner, Mark I. McCarthy
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

John R. B. Perry
Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom

Benjamin F. Voight, Noël P. Burtt, Todd Green, David Altschuler
Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Loïc Yengo, Yann Labrune, Sidonie Vivequin, Philippe Froguel, Stéphane Cauchi
CNRS UMR 8199, Genomics of Metabolic Diseases, Lille, France

Najaf Amin, Yurii Aulchenko, Albert Hofman, Cornelia van Duijn
Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands

Josée Dupuis
Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America

Josée Dupuis, Andrew D. Johnson
National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, Massachusetts, United States of America

Martha Ganser, Laura J. Scott, Michael Boehnke
Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America

Harald Grallert, Thomas Illig
Research Unit of Molecular Epidemiology, Helmholtz Zentrum Muenchen, Neuherberg, Germany

Pau Navarro, Alan F. Wright
MRC Human Genetics Unit, Medical Research Council Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom

Man Li, Anna Kottgen, Linda Kao
Johns Hopkins Bloomberg School of Public Health and Epidemiology, Baltimore, Maryland, United States of America

Lu Qi, Peter Kraft, Frank B. Hu
Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America

Valgerdur Steinthorsdottir, Gudmar Thorleifsson, Unnur Thorsteinsdottir, Kari Stefansson
deCODE Genetics, Reykjavik, Iceland

Robert A. Scott, Claudia Langenberg, Nicholas J. Wareham
MRC Epidemiology Unit, Medical Research Council, Cambridge, United Kingdom

Peter Almgren, Leif Groop
Diabetes and Endocrinology Research Unit, Department of Clinical Sciences, Lund University, Malmoe, Sweden

Dan E. Arking
McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Beverley Balkau
INSERM CESP U1018, Villejuif, France

Rafn Benediktsson, Gunnar Sigurdsson
Landspitali University Hospital, Reykjavik, Iceland

Rafn Benediktsson, Gunnar Sigurdsson
Icelandic Heart Association, Kopavogur, Iceland

Richard N. Bergman
Diabetes and Obesity Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America

Eric Boerwinkle
University of Texas Health Science Center at Houston, Human Genetics Center, Houston, Texas, United States of America

Lori Bonnycastle, Francis S. Collins
National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America

Harry Campbell, James F. Wilson
Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, United Kingdom

Guillaume Charpentier
Corbeil-Essonnes hospital, Department of Endocrinology-Diabetology, Corbeil-Essonnes, France

Christian Gieger, Ann-Kristin Petersen
Institute of Genetic Epidemiology, Helmholtz Zentrum Muenchen, Neuherberg, Germany

Samy Hadjadj
CHU Poitiers, Department of Endocrinology-Diabetology, CIC INSERM 0801, INSERM U927, University of Medical and Pharmaceutical Sciences, Poitiers, France

Christian Herder, Michael Roden
Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research, Heinrich Heine University Düsseldorf, Düsseldorf, Germany

Anna Kottgen
Freiburg University Clinic, Renal Division, Freiburg, Germany

Alisa K. Manning
Boston University School of Public Health, Boston, Massachusetts, United States of America

Karen L. Mohlke
Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, United States of America

Ben Oostra
Erasmus University Medical School, Rotterdam, The Netherlands

James Pankow
School of Public Health, Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota, United States of America

Peter P. Pramstaller
Center for Biomedicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy (Affiliated Institute of the University of Lübeck, Lübeck, Germany)

Peter P. Pramstaller
Department of Neurology, General Central Hospital, Bolzano, Italy

Peter P. Pramstaller
Department of Neurology, University of Lübeck, Lübeck, Germany

Inga Prokopenko, Mark I. McCarthy
Oxford Centre for Diabetes, Endocrinology, and Metabolism, University of Oxford, Oxford, United Kingdom

Wolfgang Rathmann
Institute of Biometrics and Epidemiology, German Diabetes Center, Leibniz Center for Diabetes Research, Heinrich Heine University Düsseldorf, Düsseldorf, Germany

Michael Roden
Department of Metabolic Diseases, University Hospital Düsseldorf, Düsseldorf, Germany

Igor Rudan
Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom

Denis Rybin
Boston University Data Coordinating Center, Boston, Massachusetts, United States of America

Rob Sladek
Department of Human Genetics, Faculty of Medicine, McGill University, Montreal, Canada

Unnur Thorsteinsdottir, Kari Stefansson
Faculty of Medicine, University of Iceland, Reykjavík, Iceland

Jaakko Tuomilehto
Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland

Jaakko Tuomilehto
South Ostrobothnia Central Hospital, Seinäjoki, Finland

Jaakko Tuomilehto
Red RECAVA Grupo RD06/0014/0015, Hospital Universitario La Paz, Madrid, Spain

Jaakko Tuomilehto
Centre for Vascular Prevention, Danube-University Krems, Krems, Austria

Andre G. Uitterlinden
Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands

Thomas Illig
Hannover Unified Biobank, Hannover Medical School, Hannover, Germany

James B. Meigs
General Medicine Division, Massachusetts General Hospital and Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America

Andrew D. Morris, Colin N. A. Palmer
Biomedical Research Institute, Ninewells Hospital and Medical School, University of Dundee, Dundee, United Kingdom

Mark I. McCarthy
Oxford NIHR Biomedical Research Centre, Churchill Hospital, Oxford, United Kingdom

Philippe Froguel
Department of Genomics of Common Diseases, Hammersmith Hospital, Imperial College London, London, United Kingdom

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Wrote the paper: JRB Perry, TM Frayling, S Cauchi. Statistical analysis: JRB Perry, BF Voight, L Yengo, N Amin, J Dupuis, M Ganser, H Grallert, P Navarro, M Li, L Qi, V Steinthorsdottir, RA Scott, P Almgren. Phenotyping/genotyping: DE Arking, Y Aulchenko, B Balkau, R Benediktsson, RN Bergman, E Boerwinkle, L Bonnycastle, NP Burtt, H Campbell, G Charpentier, FS Collins, C Gieger, T Green, S Hadjadj, AT Hattersley, C Herder, A Hofman, AD Johnson, A Kottgen, P Kraft, Y Labrune, C Langenberg, AK Manning, KL Mohlke, AP Morris, B Oostra, J Pankow, A-K Petersen, PP Pramstaller, I Prokopenko, W Rathmann, W Rayner, M Roden, I Rudan, D Rybin, LJ Scott, G Sigurdsson, R Sladek, G Thorleifsson, U Thorsteinsdottir, J Tuomilehto, AG Uitterlinden, S Vivequin, MN Weedon, AF Wright. Study design: FB Hu, T Illig, L Kao, JB Meigs, JF Wilson, K Stefansson, C van Duijn, D Altschuler, AD Morris, M Boehnke, MI McCarthy, P Froguel, CNA Palmer, NJ Wareham, L Groop, TM Frayling, S Cauchi. Involved in statistical analysis: L Yengo. Involved in the interpretation of results and editing of manuscript: all authors.