About the Authors

Leonieke M. E. van Koolwijk

Contributed equally to this work with: Leonieke M. E. van Koolwijk, Wishal D. Ramdas

Affiliations Glaucoma Service, The Rotterdam Eye Hospital, Rotterdam, The Netherlands, Department of Epidemiology, The Erasmus University Medical Center, Rotterdam, The Netherlands

Wishal D. Ramdas

Contributed equally to this work with: Leonieke M. E. van Koolwijk, Wishal D. Ramdas

Affiliations Department of Epidemiology, The Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Ophthalmology, The Erasmus University Medical Center, Rotterdam, The Netherlands

M. Kamran Ikram

Affiliations Department of Epidemiology, The Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Ophthalmology, The Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Neurology, The Erasmus University Medical Center, Rotterdam, The Netherlands

Nomdo M. Jansonius

Affiliations Department of Epidemiology, The Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Ophthalmology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

Francesca Pasutto

Affiliation Institute of Human Genetics, University Erlangen-Nuremberg, Erlangen, Germany

Pirro G. Hysi

Affiliation Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom

Stuart Macgregor

Affiliation Queensland Institute of Medical Research, Brisbane, Australia

Sarah F. Janssen

Affiliation Department of Molecular Ophthalmogenetics, The Netherlands Institute for Neuroscience (NIN), Royal Netherlands Academy of Arts and Sciences (KNAW), Amsterdam, The Netherlands

Alex W. Hewitt

Affiliation Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Australia

Ananth C. Viswanathan

Affiliation NIHR Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, United Kingdom

Jacoline B. ten Brink

Affiliation Department of Molecular Ophthalmogenetics, The Netherlands Institute for Neuroscience (NIN), Royal Netherlands Academy of Arts and Sciences (KNAW), Amsterdam, The Netherlands

S. Mohsen Hosseini

Affiliation Program in Genetics and Genome Biology, Hospital for Sick Children, Toronto, Canada

Najaf Amin

Affiliation Department of Epidemiology, The Erasmus University Medical Center, Rotterdam, The Netherlands

Dominiek D. G. Despriet

Affiliations Department of Epidemiology, The Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Ophthalmology, The Erasmus University Medical Center, Rotterdam, The Netherlands

Jacqueline J. M. Willemse-Assink

Affiliation Department of Ophthalmology, Amphia Hospital, Breda, The Netherlands

Rogier Kramer

Affiliation Department of Ophthalmology, Franciscus Hospital, Roosendaal, The Netherlands

Fernando Rivadeneira

Affiliations Department of Epidemiology, The Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Internal Medicine, The Erasmus University Medical Center, Rotterdam, The Netherlands

Maksim Struchalin

Affiliation Department of Epidemiology, The Erasmus University Medical Center, Rotterdam, The Netherlands

Yurii S. Aulchenko

Affiliation Department of Epidemiology, The Erasmus University Medical Center, Rotterdam, The Netherlands

Nicole Weisschuh

Affiliation Molecular Genetics Laboratory, University Eye Hospital, Tübingen, Germany

Matthias Zenkel

Affiliation Department of Ophthalmology, University of Erlangen-Nuremberg, Erlangen, Germany

Christian Y. Mardin

Affiliation Department of Ophthalmology, University of Erlangen-Nuremberg, Erlangen, Germany

Eugen Gramer

Affiliation University Eye Hospital, Würzburg, Germany

Ulrich Welge-Lüssen

Affiliation Department of Ophthalmology, Friedrich-Alexander University, Erlangen, Germany

Grant W. Montgomery

Affiliation Queensland Institute of Medical Research, Brisbane, Australia

Francis Carbonaro

Affiliation Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom

Terri L. Young

Affiliation Center for Human Genetics, Duke University, Durham, North Carolina, United States of America

The DCCT/EDIC Research Group
Céline Bellenguez

Affiliation Wellcome Trust Centre for Human Genetics, Oxford, United Kingdom

Peter McGuffin

Affiliation MRC Social Genetic and Developmental Psychiatry Research Centre, Institute of Psychiatry, King's College, London, United Kingdom

Paul J. Foster

Affiliation NIHR Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, United Kingdom

Fotis Topouzis

Affiliation Department of Ophthalmology, School of Medicine, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece

Paul Mitchell

Affiliation Centre for Vision Research, University of Sydney, Sydney, Australia

Jie Jin Wang

Affiliation Centre for Vision Research, University of Sydney, Sydney, Australia

Tien Y. Wong

Affiliations Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Australia, Singapore National Eye Centre and Singapore Eye Research Institute, Singapore, Singapore, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

Monika A. Czudowska

Affiliations Department of Epidemiology, The Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Ophthalmology, The Erasmus University Medical Center, Rotterdam, The Netherlands

Albert Hofman

Affiliation Department of Epidemiology, The Erasmus University Medical Center, Rotterdam, The Netherlands

Andre G. Uitterlinden

Affiliations Department of Epidemiology, The Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Internal Medicine, The Erasmus University Medical Center, Rotterdam, The Netherlands

Roger C. W. Wolfs

Affiliations Department of Epidemiology, The Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Ophthalmology, The Erasmus University Medical Center, Rotterdam, The Netherlands

Paulus T. V. M. de Jong

Affiliations Department of Molecular Ophthalmogenetics, The Netherlands Institute for Neuroscience (NIN), Royal Netherlands Academy of Arts and Sciences (KNAW), Amsterdam, The Netherlands, Department of Ophthalmology, Academic Medical Center, Amsterdam, The Netherlands

Ben A. Oostra

Affiliation Department of Clinical Genetics, The Erasmus University Medical Center, Rotterdam, The Netherlands

Andrew D. Paterson

Affiliations Program in Genetics and Genome Biology, Hospital for Sick Children, Toronto, Canada, Dalla Lana School of Public Health, University of Toronto, Toronto, Canada

Wellcome Trust Case Control Consortium 2

Membership of WTCCC2 is provided in the Acknowledgments.

David A. Mackey

Affiliation Lions Eye Institute, University of Western Australia, Centre for Ophthalmology and Visual Science, Perth, Australia

Arthur A. B. Bergen

Affiliations Department of Molecular Ophthalmogenetics, The Netherlands Institute for Neuroscience (NIN), Royal Netherlands Academy of Arts and Sciences (KNAW), Amsterdam, The Netherlands, Department of Ophthalmology, Academic Medical Center, Amsterdam, The Netherlands, Department of Clinical Genetics, Academic Medical Center, Amsterdam, the Netherlands

André Reis

Affiliation Institute of Human Genetics, University Erlangen-Nuremberg, Erlangen, Germany

Christopher J. Hammond

Affiliation Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom

Johannes R. Vingerling

Affiliations Department of Epidemiology, The Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Ophthalmology, The Erasmus University Medical Center, Rotterdam, The Netherlands

Hans G. Lemij

Affiliation Glaucoma Service, The Rotterdam Eye Hospital, Rotterdam, The Netherlands

Caroline C. W. Klaver

Affiliations Department of Epidemiology, The Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Ophthalmology, The Erasmus University Medical Center, Rotterdam, The Netherlands

Cornelia M. van Duijn

c.vanduijn@erasmusmc.nl

Affiliation Department of Epidemiology, The Erasmus University Medical Center, Rotterdam, The Netherlands

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LMEvK NMJ FR AH AGU RCWW PTVMdJ BAO JRV HGL CCWK CMvD. Performed the experiments: LMEvK WDR MKI DDGD JJMW-A RK MAC SFJ NA MS YSA AABB. Analyzed the data: LMEvK WDR CMvD. Contributed reagents/materials/analysis tools: PGH FC TLY CJH SM AWH GWM TLY DAM SMH ADP ACV CB PMcG PJF FT PM JJW TYW SFJ JBtB PTVMdJ AABB FP NW MZ CYM EG UW-L AR. Wrote the paper: LMEvK WDR CMvD. Contributed to the final version of the manuscript: all authors.