About the Authors

Maggie L. Chow

Contributed equally to this work with: Maggie L. Chow, Tiziano Pramparo

Affiliation Department of Neuroscience, NIH–UCSD Autism Center of Excellence, School of Medicine, University of California San Diego, La Jolla, California, United States of America

Tiziano Pramparo

Contributed equally to this work with: Maggie L. Chow, Tiziano Pramparo

Affiliations Department of Neuroscience, NIH–UCSD Autism Center of Excellence, School of Medicine, University of California San Diego, La Jolla, California, United States of America, Division of Medical Genetics, Department of Pediatrics and Institute of Human Genetics, School of Medicine, University of California San Francisco, San Francisco, California, United States of America

Mary E. Winn

Affiliations Scripps Genomic Medicine and The Scripps Translational Sciences Institute (STSI), La Jolla, California, United States of America, Graduate Program in Biomedical Sciences, Department of Medicine, University of California San Diego, La Jolla, California, United States of America

Cynthia Carter Barnes

Affiliation Department of Neuroscience, NIH–UCSD Autism Center of Excellence, School of Medicine, University of California San Diego, La Jolla, California, United States of America

Hai-Ri Li

Affiliation Department of Cellular and Molecular Medicine, School of Medicine, University of California San Diego, La Jolla, California, United States of America

Lauren Weiss

Affiliation Department of Psychiatry, School of Medicine, University of California San Francisco, San Francisco, California, United States of America

Jian-Bing Fan

Affiliation Illumina, San Diego, California, United States of America

Sarah Murray

Affiliation Scripps Genomic Medicine and The Scripps Translational Sciences Institute (STSI), La Jolla, California, United States of America

Craig April

Affiliation Illumina, San Diego, California, United States of America

Haim Belinson

Affiliation Division of Medical Genetics, Department of Pediatrics and Institute of Human Genetics, School of Medicine, University of California San Francisco, San Francisco, California, United States of America

Xiang-Dong Fu

These authors were joint senior authors on this work.

Affiliation Department of Cellular and Molecular Medicine, School of Medicine, University of California San Diego, La Jolla, California, United States of America

Anthony Wynshaw-Boris

These authors were joint senior authors on this work.

Affiliation Division of Medical Genetics, Department of Pediatrics and Institute of Human Genetics, School of Medicine, University of California San Francisco, San Francisco, California, United States of America

Nicholas J. Schork

nschork@scripps.edu (NJS); ecourchesne@ucsd.edu (EC)

These authors were joint senior authors on this work.

Affiliation Scripps Genomic Medicine and The Scripps Translational Sciences Institute (STSI), La Jolla, California, United States of America

Eric Courchesne

nschork@scripps.edu (NJS); ecourchesne@ucsd.edu (EC)

These authors were joint senior authors on this work.

Affiliation Department of Neuroscience, NIH–UCSD Autism Center of Excellence, School of Medicine, University of California San Diego, La Jolla, California, United States of America

Competing Interests

J-BF and CA declare stock and employment interest in Illumina, Inc.

Author Contributions

Conceived and designed the experiments: J-BF X-DF AW-B NJS EC. Performed the experiments: MLC TP H-RL CA. Analyzed the data: MLC TP MEW LW. Contributed reagents/materials/analysis tools: NJS AW-B EC X-DF LW. Wrote the paper: MLC TP AW-B NJS EC. Performed detailed review of the clinical data from the post-mortem individuals that are depicted in Table S1: CCB. Oversaw the processing of the genotyping assays: SM. Performed the second set of Bioanalyzer experiments to assess RNA quality: HB.