About the Authors

Jingjing Li

Contributed equally to this work with: Jingjing Li, Yu Liu

Address Current address: Department of Genetics, Stanford University School of Medicine, Stanford, California, United States of America

Affiliations Banting and Best Department of Medical Research, The Donnelly Centre, University of Toronto, Toronto, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Canada

Yu Liu

Contributed equally to this work with: Jingjing Li, Yu Liu

Affiliations Department of Molecular Genetics, University of Toronto, Toronto, Canada, The Center for Systems Biology, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada

Xiaofeng Xin

Address Current address: Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Affiliations Banting and Best Department of Medical Research, The Donnelly Centre, University of Toronto, Toronto, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Canada

Taehyung Simon Kim

Affiliation Banting and Best Department of Medical Research, The Donnelly Centre, University of Toronto, Toronto, Canada

Eduardo Aguiar Cabeza

Affiliation The Center for Systems Biology, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada

Jie Ren

Affiliation Department of Physics and Centre for Computational Science and Engineering, National University of Singapore, Singapore, Singapore

Rasmus Nielsen

Affiliation Departments of Integrative Biology and Statistics, University of California Berkeley, Berkeley, California, United States of America

Jeffrey L. Wrana

wrana@lunenfeld.ca (JLW); Zhaolei.Zhang@utoronto.ca (ZZ)

Affiliations Department of Molecular Genetics, University of Toronto, Toronto, Canada, The Center for Systems Biology, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada

Zhaolei Zhang

wrana@lunenfeld.ca (JLW); Zhaolei.Zhang@utoronto.ca (ZZ)

Affiliations Banting and Best Department of Medical Research, The Donnelly Centre, University of Toronto, Toronto, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Canada

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JL YL JLW ZZ. Performed the experiments: YL EAC. Analyzed the data: JL YL TSK JR XX. Wrote the paper: JL YL RN JLW ZZ.