About the Authors

Pawel K. Olszewski

Address Current address: Department of Biological Sciences, University of Waikato, Hamilton, New Zealand

Affiliations Functional Pharmacology Unit, Department of Neuroscience, Uppsala University, Uppsala, Sweden, Minnesota Obesity Center, University of Minnesota, St. Paul, Minnesota, United States of America

Jan Rozman

Affiliations German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany, Molecular Nutritional Medicine, Else Kröner-Fresenius Center and ZIEL Research Center for Nutrition and Food Sciences, Technische Universität München, Freising-Weihenstephan, Germany

Josefin A. Jacobsson

Affiliation Functional Pharmacology Unit, Department of Neuroscience, Uppsala University, Uppsala, Sweden

Birgit Rathkolb

Affiliations German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany, Chair for Molecular Animal Breeding and Biotechnology, Gene Center, Ludwig-Maximilians-Universität München, München, Germany

Siv Strömberg

Affiliation Molecular Cell Biology Unit, Department of Neuroscience, Uppsala University, Uppsala, Sweden

Wolfgang Hans

Affiliation German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

Anica Klockars

Affiliation Functional Pharmacology Unit, Department of Neuroscience, Uppsala University, Uppsala, Sweden

Johan Alsiö

Affiliation Functional Pharmacology Unit, Department of Neuroscience, Uppsala University, Uppsala, Sweden

Ulf Risérus

Affiliation Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden

Lore Becker

Affiliations German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany, Department of Neurology, Friedrich-Baur-Institut, Ludwig-Maximilians-Universität München, München, Germany

Sabine M. Hölter

Affiliations German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany, Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Developmental Genetics, Neuherberg, Germany

Ralf Elvert

Address Current address: Sanofi-Aventis GmbH, Frankfurt am Main, Germany

Affiliation German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

Nicole Ehrhardt

Address Current address: Department of Medical Genetics, Cedars-Sinai Medical Center, Los Angeles, California, United States of America

Affiliation German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

Valérie Gailus-Durner

Affiliation German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

Helmut Fuchs

Affiliation German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

Robert Fredriksson

Affiliation Functional Pharmacology Unit, Department of Neuroscience, Uppsala University, Uppsala, Sweden

Eckhard Wolf

Affiliation Chair for Molecular Animal Breeding and Biotechnology, Gene Center, Ludwig-Maximilians-Universität München, München, Germany

Thomas Klopstock

Affiliation Department of Neurology, Friedrich-Baur-Institut, Ludwig-Maximilians-Universität München, München, Germany

Wolfgang Wurst

Affiliations Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Developmental Genetics, Neuherberg, Germany, Max-Planck-Institute for Psychiatry, München, Germany, Technical University München-Weihenstephan, Lehrstuhl für Entwicklungsgenetik c/o Helmholtz Zentrum München, Neuherberg, Germany, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE) Munich, Germany

Allen S. Levine

Affiliation Minnesota Obesity Center, University of Minnesota, St. Paul, Minnesota, United States of America

Claude Marcus

Affiliation Department for Clinical Science, Intervention, and Technology, Karolinska Institutet, Division of Pediatrics, National Childhood Obesity Centre, Stockholm, Sweden

Martin Hrabě de Angelis

Affiliations German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany, Lehrstuhl für Experimentelle Genetik, Technische Universität München, Freising-Weihenstephan, Germany

Martin Klingenspor

Affiliation Molecular Nutritional Medicine, Else Kröner-Fresenius Center and ZIEL Research Center for Nutrition and Food Sciences, Technische Universität München, Freising-Weihenstephan, Germany

Helgi B. Schiöth

These authors were joint senior authors on this work.

Affiliation Functional Pharmacology Unit, Department of Neuroscience, Uppsala University, Uppsala, Sweden

Manfred W. Kilimann

manfred.kilimann@neuro.uu.se

These authors were joint senior authors on this work.

Affiliation Molecular Cell Biology Unit, Department of Neuroscience, Uppsala University, Uppsala, Sweden

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MWK PKO ASL CM UR JR WW TK EW MK VG-D HF MHdA. Performed the experiments: JAJ SS AK JA PKO JR RE NE BR WH LB SMH. Analyzed the data: JAJ RF JR RE MK BR WH LB SMH MWK. Wrote the paper: PKO HBS JR MK MWK.