About the Authors

David B. Berry

Affiliation Laboratory of Genetics, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

Qiaoning Guan

Address Current address: University of California Berkeley, Berkeley, California, United States of America

Affiliation Laboratory of Genetics, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

James Hose

Affiliation Laboratory of Genetics, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

Suraiya Haroon

Affiliation Laboratory of Genetics, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

Marinella Gebbia

Affiliations Terrance Donnelly Centre for Cellular and Biomolecular Research, Toronto, Canada, Department of Pharmaceutical Sciences, University of Toronto, Toronto, Canada

Lawrence E. Heisler

Affiliations Terrance Donnelly Centre for Cellular and Biomolecular Research, Toronto, Canada, Department of Pharmaceutical Sciences, University of Toronto, Toronto, Canada

Corey Nislow

Affiliations Terrance Donnelly Centre for Cellular and Biomolecular Research, Toronto, Canada, Banting and Best Department of Medical Research, University of Toronto, Toronto, Canada

Guri Giaever

Affiliations Terrance Donnelly Centre for Cellular and Biomolecular Research, Toronto, Canada, Department of Pharmaceutical Sciences, University of Toronto, Toronto, Canada

Audrey P. Gasch

agasch@wisc.edu

Affiliations Laboratory of Genetics, University of Wisconsin–Madison, Madison, Wisconsin, United States of America, Genome Center of Wisconsin, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived experiments: DBB APG. Data analysis, validation, and interpretation: DBB. Designed and conducted selection experiments: DBB QG SH. Designed barcode array hybridizations: CN GG. Performed barcode array hybridizations: MG. Analyzed barcode array hybridizations: LEH. Performed qPCR and assisted in strain validations: JH. Wrote the manuscript: DBB APG.