About the Authors

Rozenn N. Lemaitre, Joshua C. Bis, Bruce M. Psaty, David S. Siscovick
Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, United States of America

Toshiko Tanaka, Luigi Ferrucci
Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America

Weihong Tang, Lu-Chen Weng, David R. Jacobs Jr., Lyn M. Steffen
Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota, United States of America

Ani Manichaikul
Center for Public Health Genomics, Division of Biostatistics and Epidemiology, University of Virginia, Charlottesville, Virginia, United States of America

Millennia Foy, Xiangjun Gu, Myriam Fornage
Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, Texas, United States of America

Edmond K. Kabagambe, Donna K. Arnett
Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

Jennifer A. Nettleton, Myriam Fornage
Division of Epidemiology, Human Genetics, and Environmental Sciences, University of Texas Health Science Center at Houston, Houston, Texas, United States of America

Irena B. King
Department of Internal Medicine, University of New Mexico, Albuquerque, New Mexico, United States of America

Sayanti Bhattacharya
Duke Global Health Institute, Duke University, Durham, North Carolina, United States of America

Stefania Bandinelli
Geriatric Unit, Azienda Sanitaria Firenze (ASF), Florence, Italy

Stephen S. Rich
Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, United States of America

Antonio Cherubini
Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy

Barbara McKnight, Kenneth Rice, Cathy C. Laurie
Department of Biostatistics, School of Public Health, University of Washington, Seattle, Washington, United States of America

Shuang Liang, Michael Y. Tsai
Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, United States of America

Thomas Lumley
Department of Statistics, University of Auckland, Auckland, New Zealand

Brian L. Browning
Department of Medicine, Division of Medical Genetics, University of Washington, Seattle, Washington, United States of America

Bruce M. Psaty
Departments of Epidemiology and Health Services, University of Washington, Seattle, Washington, United States of America

Bruce M. Psaty
Group Health Research Institute, Group Health Cooperative, Seattle, Washington, United States of America

Yii-Der I. Chen
Medical Genetics Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America

Yechiel Friedlander
Unit of Epidemiology, School of Public Health, Hebrew University-Hadassah, Jerusalem, Israel

Luc Djousse
Division of Aging, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Luc Djousse
Boston VA Healthcare System, Boston, Massachusetts, United States of America

Jason H. Y. Wu, Dariush Mozaffarian
Department of Epidemiology and Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America

Jason H. Y. Wu
School of Medicine and Pharmacology, University of Western Australia, Perth, Australia

David S. Siscovick
Department of Epidemiology, School of Public Health, University of Washington, Seattle, Washington, United States of America

André G. Uitterlinden
Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands

Dariush Mozaffarian
Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Corresponding Author

rozenl@u.washington.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RN Lemaitre, T Tanaka, BM Psaty, DS Siscovick, D Mozaffarian. Analyzed the data: RN Lemaitre, T Tanaka, W Tang, A Manichaikul, M Foy, S Bhattacharya, JC Bis, B McKnight, K Rice, CC Laurie, T Lumley. Contributed reagents/materials/analysis tools: IB King, L-C Weng, S Bandinelli, SS Rich, DR Jacobs Jr, A Cherubini, S Liang, X Gu, BL Browning, BM Psaty, Y-DI Chen, DS Siscovick, AG Uitterlinden, L Ferrucci, M Fornage, MY Tsai, D Mozaffarian, LM Steffen. Wrote the paper: RN Lemaitre, T Tanaka, W Tang, A Manichaikul, M Foy, EK Kabagambe, JA Nettleton, Y Friedlander, L Djousse, JHY Wu, DK Arnett.