About the Authors

Shao-Qing Kuang

Contributed equally to this work with: Shao-Qing Kuang, Dong-Chuan Guo, Siddharth K. Prakash

Affiliation Department of Internal Medicine, University of Texas Health Science Center at Houston, Houston, Texas, United States of America

Dong-Chuan Guo

Contributed equally to this work with: Shao-Qing Kuang, Dong-Chuan Guo, Siddharth K. Prakash

Affiliation Department of Internal Medicine, University of Texas Health Science Center at Houston, Houston, Texas, United States of America

Siddharth K. Prakash

Contributed equally to this work with: Shao-Qing Kuang, Dong-Chuan Guo, Siddharth K. Prakash

Affiliation Department of Internal Medicine, University of Texas Health Science Center at Houston, Houston, Texas, United States of America

Merry-Lynn N. McDonald

Affiliation Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

Ralph J. Johnson

Affiliation Department of Internal Medicine, University of Texas Health Science Center at Houston, Houston, Texas, United States of America

Min Wang

Affiliation Department of Internal Medicine, University of Texas Health Science Center at Houston, Houston, Texas, United States of America

Ellen S. Regalado

Affiliation Department of Internal Medicine, University of Texas Health Science Center at Houston, Houston, Texas, United States of America

Ludivine Russell

Affiliations Division of Cardiothoracic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas, United States of America, Cardiovascular Surgery, Texas Heart Institute at St. Luke's Episcopal Hospital, Houston, Texas, United States of America

Jiu-Mei Cao

Affiliation Department of Internal Medicine, University of Texas Health Science Center at Houston, Houston, Texas, United States of America

Callie Kwartler

Affiliation Department of Internal Medicine, University of Texas Health Science Center at Houston, Houston, Texas, United States of America

Kurt Fraivillig

Affiliation Department of Internal Medicine, University of Texas Health Science Center at Houston, Houston, Texas, United States of America

Joseph S. Coselli

Affiliations Division of Cardiothoracic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas, United States of America, Cardiovascular Surgery, Texas Heart Institute at St. Luke's Episcopal Hospital, Houston, Texas, United States of America

Hazim J. Safi

Affiliation Department of Cardiothoracic and Vascular Surgery, University of Texas Health Science Center at Houston, Houston, Texas, United States of America

Anthony L. Estrera

Affiliation Department of Cardiothoracic and Vascular Surgery, University of Texas Health Science Center at Houston, Houston, Texas, United States of America

Suzanne M. Leal

Affiliation Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

Scott A. LeMaire

Affiliations Division of Cardiothoracic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas, United States of America, Cardiovascular Surgery, Texas Heart Institute at St. Luke's Episcopal Hospital, Houston, Texas, United States of America

John W. Belmont

Affiliation Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

Dianna M. Milewicz

Dianna.M.Milewicz@uth.tmc.edu

Affiliations Department of Internal Medicine, University of Texas Health Science Center at Houston, Houston, Texas, United States of America, Internal Medicine Service, Texas Heart Institute at St. Luke's Episcopal Hospital, Houston, Texas, United States of America

GenTAC Investigators

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SML SAL JWB DMM. Performed the experiments: S-QK D-CG SKP MW J-MC CK KF. Analyzed the data: SKP M-LNM SML DMM. Contributed reagents/materials/analysis tools: LR RJJ. Wrote the paper: S-QK D-CG SKP DMM. Provided clinical data and DNA samples: JSC HJS ALE ESR DMM GenTAC Investigators.