About the Authors

Guy M. Lenk

Affiliation Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, United States of America

Cole J. Ferguson

Affiliation Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, United States of America

Clement Y. Chow

Contributed equally to this work with: Clement Y. Chow, Natsuko Jin

Current address: Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, United States of America

Affiliation Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, United States of America

Natsuko Jin

Contributed equally to this work with: Clement Y. Chow, Natsuko Jin

Affiliation Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, United States of America

Julie M. Jones

Affiliation Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, United States of America

Adrienne E. Grant

Affiliation Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, United States of America

Sergey N. Zolov

Affiliation Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, United States of America

Jesse J. Winters

Affiliation Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America

Roman J. Giger

Affiliations Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America, Department of Neurology, University of Michigan, Ann Arbor, Michigan, United States of America

James J. Dowling

Affiliation Department of Neurology, University of Michigan, Ann Arbor, Michigan, United States of America

Lois S. Weisman

Affiliations Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, United States of America, Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America

Miriam H. Meisler

meislerm@umich.edu

Affiliation Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: GML CJF CYC LSW MHM. Performed the experiments: GML CJF CYC NJ JMJ AEG SNZ JJW. Analyzed the data: GML CJF CYC NJ JMJ AEG SNZ JJW RJG JJD LSW MHM. Wrote the paper: GML MHM.