About the Authors
- Gordan Lauc
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Contributed equally to this work with: Gordan Lauc, Abdelkader Essafi, Jennifer E. Huffman, Caroline Hayward
Affiliations Glycobiology Laboratory, Genos Ltd., Zagreb, Croatia, Department of Biochemistry and Molecular Biology, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, Croatia
- Abdelkader Essafi
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Contributed equally to this work with: Gordan Lauc, Abdelkader Essafi, Jennifer E. Huffman, Caroline Hayward
Affiliation Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, United Kingdom
- Jennifer E. Huffman
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Contributed equally to this work with: Gordan Lauc, Abdelkader Essafi, Jennifer E. Huffman, Caroline Hayward
Affiliation Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, United Kingdom
- Caroline Hayward
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Contributed equally to this work with: Gordan Lauc, Abdelkader Essafi, Jennifer E. Huffman, Caroline Hayward
Affiliation Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, United Kingdom
- Ana Knežević
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Affiliation Department of Biochemistry and Molecular Biology, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, Croatia
- Jayesh J. Kattla
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Affiliations National Institute for Bioprocessing Research and Training, Dublin-Oxford Glycobiology Lab, Conway Institute, University College Dublin, Dublin, Ireland, Conway Institute, University College Dublin, Dublin, Ireland
- Ozren Polašek
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Affiliations Gen Info Ltd., Zagreb, Croatia, Medical School, University of Zagreb, Zagreb, Croatia
- Olga Gornik
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Affiliation Department of Biochemistry and Molecular Biology, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, Croatia
- Veronique Vitart
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Affiliation Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, United Kingdom
- Jodie L. Abrahams
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Affiliations National Institute for Bioprocessing Research and Training, Dublin-Oxford Glycobiology Lab, Conway Institute, University College Dublin, Dublin, Ireland, Conway Institute, University College Dublin, Dublin, Ireland
- Maja Pučić
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Affiliation Glycobiology Laboratory, Genos Ltd., Zagreb, Croatia
- Mislav Novokmet
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Affiliation Glycobiology Laboratory, Genos Ltd., Zagreb, Croatia
- Irma Redžić
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Affiliation Department of Biochemistry and Molecular Biology, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, Croatia
- Susan Campbell
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Affiliation Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, United Kingdom
- Sarah H. Wild
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Affiliation Centre for Population Health Sciences, The University of Edinburgh Medical School, Edinburgh, United Kingdom
- Fran Borovečki
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Affiliation Medical School, University of Zagreb, Zagreb, Croatia
- Wei Wang
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Affiliations School of Public Health and Family Medicine, Capital Medical University, Beijing, China, Graduate School of the Chinese Academy of Sciences, Beijing, China, Croatian Centre for Global Health, University of Split Medical School, Split, Croatia
- Ivana Kolčić
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Affiliation Medical School, University of Zagreb, Zagreb, Croatia
- Lina Zgaga
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Affiliation Medical School, University of Zagreb, Zagreb, Croatia
- Ulf Gyllensten
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Affiliation Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden
- James F. Wilson
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¶These authors also contributed equally to this work.
Affiliation Centre for Population Health Sciences, The University of Edinburgh Medical School, Edinburgh, United Kingdom
- Alan F. Wright
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¶These authors also contributed equally to this work.
Affiliation Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, United Kingdom
- Nicholas D. Hastie
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¶These authors also contributed equally to this work.
Affiliation Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, United Kingdom
- Harry Campbell
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¶These authors also contributed equally to this work.
Affiliation Centre for Population Health Sciences, The University of Edinburgh Medical School, Edinburgh, United Kingdom
- Pauline M. Rudd
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¶These authors also contributed equally to this work.
Affiliations National Institute for Bioprocessing Research and Training, Dublin-Oxford Glycobiology Lab, Conway Institute, University College Dublin, Dublin, Ireland, Conway Institute, University College Dublin, Dublin, Ireland
- Igor Rudan
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* E-mail: irudan@hotmail.com
¶These authors also contributed equally to this work.
Affiliations Centre for Population Health Sciences, The University of Edinburgh Medical School, Edinburgh, United Kingdom, Croatian Centre for Global Health, University of Split Medical School, Split, Croatia
Competing Interests
The authors have declared that no competing interests exist.
Author Contributions
Conceived and designed the experiments: G Lauc, A Essafi, C Hayward, A Knezevic, O Gornik, U Gyllensten, JF Wilson, AF Wright, ND Hastie, H Campbell, PM Rudd, I Rudan. Performed the experiments: A Essafi, JE Huffman, A Knezevic, JJ Kattla, O Polasek, V Vitart, JL Abrahams, M Pucic, M Novokmet, I Redzic, SH Wild, F Borovecki, I Kolcic, L Zgaga. Analyzed the data: G Lauc, A Essafi, JE Huffman, C Hayward, A Knezevic, JJ Kattla, O Polasek, O Gornik, V Vitart, JL Abrahams, M Pucic, M Novokmet, I Redzic, S Campbell, SH Wild, F Borovecki, W Wang, I Kolcic, L Zgaga, U Gyllensten, JF Wilson, AF Wright, ND Hastie, H Campbell, PM Rudd, I Rudan. Contributed reagents/materials/analysis tools: G Lauc, C Hayward, O Polasek, V Vitart, S Campbell, F Borovecki, W Wang, I Kolcic, L Zgaga, U Gyllensten, JF Wilson, AF Wright, ND Hastie, H Campbell, PM Rudd, I Rudan. Wrote the paper: G Lauc, A Essafi, JE Huffman, C Hayward, O Gornik, V Vitart, U Gyllensten, JF Wilson, AF Wright, ND Hastie, H Campbell, PM Rudd, I Rudan. Led the writing of the paper: I Rudan, G Lauc. Performed functional genomic studies: A Essafi. Carried out the genotyping and performed statistical analyses: JE Huffman, C Hayward, V Vitart, S Campbell, SH Wild, F Borovecki. Performed laboratory analyses of glycans: A Knezevic, JJ Kattla, O Gornik, JL Abrahams, M Pucic, M Novokmet, I Rudan. Performed field work and constructed genealogies in Croatia: O Polasek, I Kolcic, L Zgaga. Assisted in writing of the paper and checked the manuscript for important intellectual content: W Wang, U Gyllensten, JF Wilson, AF Wright, ND Hastie, H Campbell, PM Rudd. Designed the study: U Gyllensten, JF Wilson, AF Wright, ND Hastie, H Campbell, PM Rudd, I Rudan, G Lauc.