About the Authors

Gordan Lauc

Contributed equally to this work with: Gordan Lauc, Abdelkader Essafi, Jennifer E. Huffman, Caroline Hayward

Affiliations Glycobiology Laboratory, Genos Ltd., Zagreb, Croatia, Department of Biochemistry and Molecular Biology, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, Croatia

Abdelkader Essafi

Contributed equally to this work with: Gordan Lauc, Abdelkader Essafi, Jennifer E. Huffman, Caroline Hayward

Affiliation Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, United Kingdom

Jennifer E. Huffman

Contributed equally to this work with: Gordan Lauc, Abdelkader Essafi, Jennifer E. Huffman, Caroline Hayward

Affiliation Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, United Kingdom

Caroline Hayward

Contributed equally to this work with: Gordan Lauc, Abdelkader Essafi, Jennifer E. Huffman, Caroline Hayward

Affiliation Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, United Kingdom

Ana Knežević

Affiliation Department of Biochemistry and Molecular Biology, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, Croatia

Jayesh J. Kattla

Affiliations National Institute for Bioprocessing Research and Training, Dublin-Oxford Glycobiology Lab, Conway Institute, University College Dublin, Dublin, Ireland, Conway Institute, University College Dublin, Dublin, Ireland

Ozren Polašek

Affiliations Gen Info Ltd., Zagreb, Croatia, Medical School, University of Zagreb, Zagreb, Croatia

Olga Gornik

Affiliation Department of Biochemistry and Molecular Biology, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, Croatia

Veronique Vitart

Affiliation Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, United Kingdom

Jodie L. Abrahams

Affiliations National Institute for Bioprocessing Research and Training, Dublin-Oxford Glycobiology Lab, Conway Institute, University College Dublin, Dublin, Ireland, Conway Institute, University College Dublin, Dublin, Ireland

Maja Pučić

Affiliation Glycobiology Laboratory, Genos Ltd., Zagreb, Croatia

Mislav Novokmet

Affiliation Glycobiology Laboratory, Genos Ltd., Zagreb, Croatia

Irma Redžić

Affiliation Department of Biochemistry and Molecular Biology, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, Croatia

Susan Campbell

Affiliation Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, United Kingdom

Sarah H. Wild

Affiliation Centre for Population Health Sciences, The University of Edinburgh Medical School, Edinburgh, United Kingdom

Fran Borovečki

Affiliation Medical School, University of Zagreb, Zagreb, Croatia

Wei Wang

Affiliations School of Public Health and Family Medicine, Capital Medical University, Beijing, China, Graduate School of the Chinese Academy of Sciences, Beijing, China, Croatian Centre for Global Health, University of Split Medical School, Split, Croatia

Ivana Kolčić

Affiliation Medical School, University of Zagreb, Zagreb, Croatia

Lina Zgaga

Affiliation Medical School, University of Zagreb, Zagreb, Croatia

Ulf Gyllensten

Affiliation Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden

James F. Wilson

These authors also contributed equally to this work.

Affiliation Centre for Population Health Sciences, The University of Edinburgh Medical School, Edinburgh, United Kingdom

Alan F. Wright

These authors also contributed equally to this work.

Affiliation Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, United Kingdom

Nicholas D. Hastie

These authors also contributed equally to this work.

Affiliation Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, United Kingdom

Harry Campbell

These authors also contributed equally to this work.

Affiliation Centre for Population Health Sciences, The University of Edinburgh Medical School, Edinburgh, United Kingdom

Pauline M. Rudd

These authors also contributed equally to this work.

Affiliations National Institute for Bioprocessing Research and Training, Dublin-Oxford Glycobiology Lab, Conway Institute, University College Dublin, Dublin, Ireland, Conway Institute, University College Dublin, Dublin, Ireland

Igor Rudan

irudan@hotmail.com

These authors also contributed equally to this work.

Affiliations Centre for Population Health Sciences, The University of Edinburgh Medical School, Edinburgh, United Kingdom, Croatian Centre for Global Health, University of Split Medical School, Split, Croatia

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: G Lauc, A Essafi, C Hayward, A Knezevic, O Gornik, U Gyllensten, JF Wilson, AF Wright, ND Hastie, H Campbell, PM Rudd, I Rudan. Performed the experiments: A Essafi, JE Huffman, A Knezevic, JJ Kattla, O Polasek, V Vitart, JL Abrahams, M Pucic, M Novokmet, I Redzic, SH Wild, F Borovecki, I Kolcic, L Zgaga. Analyzed the data: G Lauc, A Essafi, JE Huffman, C Hayward, A Knezevic, JJ Kattla, O Polasek, O Gornik, V Vitart, JL Abrahams, M Pucic, M Novokmet, I Redzic, S Campbell, SH Wild, F Borovecki, W Wang, I Kolcic, L Zgaga, U Gyllensten, JF Wilson, AF Wright, ND Hastie, H Campbell, PM Rudd, I Rudan. Contributed reagents/materials/analysis tools: G Lauc, C Hayward, O Polasek, V Vitart, S Campbell, F Borovecki, W Wang, I Kolcic, L Zgaga, U Gyllensten, JF Wilson, AF Wright, ND Hastie, H Campbell, PM Rudd, I Rudan. Wrote the paper: G Lauc, A Essafi, JE Huffman, C Hayward, O Gornik, V Vitart, U Gyllensten, JF Wilson, AF Wright, ND Hastie, H Campbell, PM Rudd, I Rudan. Led the writing of the paper: I Rudan, G Lauc. Performed functional genomic studies: A Essafi. Carried out the genotyping and performed statistical analyses: JE Huffman, C Hayward, V Vitart, S Campbell, SH Wild, F Borovecki. Performed laboratory analyses of glycans: A Knezevic, JJ Kattla, O Gornik, JL Abrahams, M Pucic, M Novokmet, I Rudan. Performed field work and constructed genealogies in Croatia: O Polasek, I Kolcic, L Zgaga. Assisted in writing of the paper and checked the manuscript for important intellectual content: W Wang, U Gyllensten, JF Wilson, AF Wright, ND Hastie, H Campbell, PM Rudd. Designed the study: U Gyllensten, JF Wilson, AF Wright, ND Hastie, H Campbell, PM Rudd, I Rudan, G Lauc.