About the Authors

Sanne Nygaard, Anders Krogh
Bioinformatics Centre, University of Copenhagen, Copenhagen, Denmark

Sanne Nygaard, Anders Krogh
Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen, Denmark

Sanne Nygaard
Center for Social Evolution, University of Copenhagen, Copenhagen, Denmark

Alexander Braunstein, Jon McAuliffe
Statistics Department, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Alexander Braunstein
Google, Inc., Mountain View, California, United States of America

Gareth Malsen, Paul P. Gardner, Thomas D. Otto, Arnab Pain, Matthew Berriman, Emmanouil T. Dermitzakis, Daniel C. Jeffares
Wellcome Trust Sanger Institute, Cambridge, United Kingdom

Stijn Van Dongen
RNA Genomics, European Bioinformatics Institute, Cambridge, United Kingdom

Arnab Pain
Computational Bioscience Research Center, King Abdullah University of Science and Technology, Jeddah, Saudi Arabia

Emmanouil T. Dermitzakis
Department of Genetic Medicine and Development, University of Geneva, Geneva, Switzerland

Daniel C. Jeffares
Department of Genetics, Evolution and Environment, University College London, United Kingdom

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ETD DCJ. Performed the experiments: SN AB GM DCJ. Analyzed the data: SN SvD PPG TDO JM ETD DCJ. Contributed reagents/materials/analysis tools: AK TDO AP MB JM DCJ. Wrote the paper: SN ETD DCJ. Identified and characterized CEs, ran SISSIz, identified SNPs, conducted polymorphism analysis, collated analysis: DCJ. Conducted divergence and constraint analysis, integrated genome annotations and alignments, ran RNAz: SN. Created alignments: AB JM. Obtained and mapped P. falciparum reads to the reference: GM. Assisted with RNA-Seq transcriptome analysis: TDO. Contributed suggestions for analysis: AP MB. Initiated the study, assisted with data analysis: ETD.