About the Authors

David J. Speca, Daisuke Chihara, Amir M. Ashique, M. Scott Bowers, Jonathan T. Pierce-Shimomura, Jungsoo Lee, Andrew S. Peterson, Steven L. McIntire
Department of Neurology and the Ernest Gallo Clinic and Research Center, University of California San Francisco, Emeryville, California, United States of America

Nusrat Rabbee, Terence P. Speed
Department of Statistics, University of California Berkeley, Berkeley, California, United States of America

Rodrigo J. Gularte, James Chitwood, Juan F. Medrano
Department of Animal Science, University of California Davis, Davis, California, United States of America

Mark Liao, James M. Sonner, Edmond I. Eger II
Department of Anesthesia and Perioperative Care, University of California San Francisco, San Francisco, California, United States of America

Corresponding Authors

Competing Interests

EIE is a paid consultant of Baxter Healthcare.

Author Contributions

Conceived and designed the experiments: DJS TPS JFM EIEI ASP SLM. Performed the experiments: DJS DC AMA MSB JL NR RJG JC ML JMS EIEI. Analyzed the data: DJS DC MSB JTPS JL NR TPS RJG JFM JMS EIEI ASP SLM. Wrote the paper: DJS DC AMA MSB JTPS JL TPS RJG JC JFM EIEI ASP SLM.