About the Authors

Jirong Long

Affiliation Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Qiuyin Cai

Affiliation Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Xiao-Ou Shu

Affiliation Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Shimian Qu

Affiliation Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Chun Li

Affiliation Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Ying Zheng

Affiliation Shanghai Center for Disease Control and Prevention, Shanghai, China

Kai Gu

Affiliation Shanghai Center for Disease Control and Prevention, Shanghai, China

Wenjing Wang

Affiliation Shanghai Center for Disease Control and Prevention, Shanghai, China

Yong-Bing Xiang

Affiliation Department of Epidemiology, Shanghai Cancer Institute, Shanghai, China

Jiarong Cheng

Affiliation Department of Epidemiology, Shanghai Cancer Institute, Shanghai, China

Kexin Chen

Affiliation Department of Epidemiology and Biostatistics, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China

Lina Zhang

Affiliation Department of Epidemiology and Biostatistics, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China

Hong Zheng

Affiliation Department of Epidemiology and Biostatistics, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China

Chen-Yang Shen

Affiliation Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan

Chiun-Sheng Huang

Affiliation Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan

Ming-Feng Hou

Affiliation Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan

Hongbing Shen

Affiliation Department of Epidemiology and Biostatistics, Nanjing Medical University, Nanjing, China

Zhibin Hu

Affiliation Department of Epidemiology and Biostatistics, Nanjing Medical University, Nanjing, China

Furu Wang

Affiliation Department of Epidemiology and Biostatistics, Nanjing Medical University, Nanjing, China

Sandra L. Deming

Affiliation Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Mark C. Kelley

Affiliation Division of Surgical Oncology, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Martha J. Shrubsole

Affiliation Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Ui Soon Khoo

Affiliation Department of Pathology, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China

Kelvin Y. K. Chan

Affiliation Division of Surgical Oncology, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Sum Yin Chan

Affiliation Department of Pathology, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China

Christopher A. Haiman

Affiliation Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California, United States of America

Brian E. Henderson

Affiliation Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California, United States of America

Loic Le Marchand

Affiliation Epidemiology Program, Cancer Research Center, University of Hawaii, Honolulu, Hawaii, United States of America

Motoki Iwasaki

Affiliation Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan

Yoshio Kasuga

Affiliation Department of Surgery, Nagano Matsushiro General Hospital, Nagano, Japan

Shoichiro Tsugane

Affiliation Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan

Keitaro Matsuo

Affiliation Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan

Kazuo Tajima

Affiliation Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan

Hiroji Iwata

Affiliation Department of Breast Oncology, Aichi Cancer Center Central Hospital, Nagoya, Japan

Bo Huang

Affiliation Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Jiajun Shi

Affiliation Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Guoliang Li

Affiliation Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Wanqing Wen

Affiliation Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Yu-Tang Gao

Affiliation Department of Epidemiology, Shanghai Cancer Institute, Shanghai, China

Wei Lu

Affiliation Shanghai Center for Disease Control and Prevention, Shanghai, China

Wei Zheng

wei.zheng@vanderbilt.edu

Affiliation Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: W Zheng. Performed the experiments: Q Cai, S Qul, B Huang. Wrote the paper: J Long, Q Cai, XO Shu, S Qul, W Zheng. Designed and directed the study: W Zheng. Drafted the manuscript: J Long, W Zheng, Q Cai, XO Shu, S Qul. Directed the studies that contributed data to consortium or contributed to data and biological collection of these original studies: XO Shu, Y Zheng, K Gu, W Wang, YB Xiang, J Cheng, K Chen, L Zhang, H Zheng, CY Shen, CS Huang, MF Hou, H Shen, Z Hu, F Wang, SL Deming, MC Kelley, MJ Shrubsole, US Khoo, KYK Chan, SY Chan, CA Haiman, BE Henderson, L Le Marchand, M Iwasaki, Y Kasuga, S Tsugane, K Matsuo, K Tajima, H Iwata, YT Gao, W Lu, W Zheng. Coordinated the genetic study: J Long. Managed the genotyping data: J Long. Performed statistical analyses: J Long, C Li, W Wen. Directed lab operations: Q Cai. Conducted in vitro functional experiments: Q Cai, S Qul, B Huang. Performed genotyping assays: J Shi, G Li.