About the Authors

J. Raphael Gibbs

Contributed equally to this work with: J. Raphael Gibbs, Marcel P. van der Brug, Dena G. Hernandez

Affiliations Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America, Department of Molecular Neuroscience and Reta Lila Weston Laboratories, Institute of Neurology, University College London, London, United Kingdom

Marcel P. van der Brug

Contributed equally to this work with: J. Raphael Gibbs, Marcel P. van der Brug, Dena G. Hernandez

Affiliations Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America, Department of Molecular and Integrative Neurosciences, The Scripps Research Institute, Jupiter, Florida, United States of America

Dena G. Hernandez

Contributed equally to this work with: J. Raphael Gibbs, Marcel P. van der Brug, Dena G. Hernandez

Affiliations Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America, Department of Molecular Neuroscience and Reta Lila Weston Laboratories, Institute of Neurology, University College London, London, United Kingdom

Bryan J. Traynor

Affiliation Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America

Michael A. Nalls

Affiliation Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America

Shiao-Lin Lai

Affiliations Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America, Department of Molecular Neuroscience and Reta Lila Weston Laboratories, Institute of Neurology, University College London, London, United Kingdom

Sampath Arepalli

Affiliation Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America

Allissa Dillman

Affiliation Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America

Ian P. Rafferty

Affiliation Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America

Juan Troncoso

Affiliation Division of Neuropathology, Department of Pathology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America

Robert Johnson

Affiliation National Institute of Child Heath and Human Development Brain and Tissue Bank for Developmental Disorders, University of Maryland Medical School, Baltimore, Maryland, United States of America

H. Ronald Zielke

Affiliation National Institute of Child Heath and Human Development Brain and Tissue Bank for Developmental Disorders, University of Maryland Medical School, Baltimore, Maryland, United States of America

Luigi Ferrucci

Affiliation Clinical Research Branch, National Institute on Aging, Baltimore, Maryland, United States of America

Dan L. Longo

Affiliation Lymphocyte Cell Biology Unit, Laboratory of Immunology, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America

Mark R. Cookson

cookson@mail.nih.gov (MRC); singleta@mail.nih.gov (ABS)

Affiliation Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America

Andrew B. Singleton

cookson@mail.nih.gov (MRC); singleta@mail.nih.gov (ABS)

Affiliation Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JRG MPvdB DGH BJT DLL MRC ABS. Performed the experiments: MPvdB DGH BJT SLL SA AD IPR JT. Analyzed the data: JRG MAN ABS. Contributed reagents/materials/analysis tools: JT RJ HRZ LF. Wrote the paper: JRG MRC ABS.