About the Authors
- Hua Zhong
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Affiliation Department of Genetics, Rosetta Inpharmatics, Seattle, Washington, United States of America
- John Beaulaurier
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Affiliation Department of Genetics, Rosetta Inpharmatics, Seattle, Washington, United States of America
- Pek Yee Lum
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Affiliation Department of Genetics, Rosetta Inpharmatics, Seattle, Washington, United States of America
- Cliona Molony
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Affiliation Department of Genetics, Rosetta Inpharmatics, Seattle, Washington, United States of America
- Xia Yang
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Affiliation Department of Genetics, Rosetta Inpharmatics, Seattle, Washington, United States of America
- Douglas J. MacNeil
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Affiliation Department of Metabolic Disorders, Merck and Co., Rahway, New Jersey, United States of America
- Drew T. Weingarth
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Affiliation Department of Metabolic Disorders, Merck and Co., Rahway, New Jersey, United States of America
- Bin Zhang
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Affiliation Department of Genetics, Rosetta Inpharmatics, Seattle, Washington, United States of America
- Danielle Greenawalt
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Affiliation Department of Genetics, Rosetta Inpharmatics, Seattle, Washington, United States of America
- Radu Dobrin
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Affiliation Department of Genetics, Rosetta Inpharmatics, Seattle, Washington, United States of America
- Ke Hao
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Affiliation Department of Genetics, Rosetta Inpharmatics, Seattle, Washington, United States of America
- Sangsoon Woo
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Affiliation Department of Biostatistics, University of Washington, Seattle, Washington, United States of America
- Christine Fabre-Suver
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Affiliation Department of Genetics, Rosetta Inpharmatics, Seattle, Washington, United States of America
- Su Qian
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Affiliation Department of Metabolic Disorders, Merck and Co., Rahway, New Jersey, United States of America
- Michael R. Tota
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Affiliation Department of Metabolic Disorders, Merck and Co., Rahway, New Jersey, United States of America
- Mark P. Keller
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Affiliation Department of Biochemistry, University of Wisconsin, Madison, Wisconsin, United States of America
- Christina M. Kendziorski
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Affiliation Department of Biostatistics and Medical Informatics, University of Wisconsin, Madison, Wisconsin, United States of America
- Brian S. Yandell
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Affiliation Department of Statistics, University of Wisconsin, Madison, Wisconsin, United States of America
- Victor Castro
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Affiliation Massachusetts General Hospital Weight Center, Boston, Massachusetts, United States of America
- Alan D. Attie
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Affiliation Department of Biochemistry, University of Wisconsin, Madison, Wisconsin, United States of America
- Lee M. Kaplan
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Affiliations Massachusetts General Hospital Weight Center, Boston, Massachusetts, United States of America, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America
- Eric E. Schadt
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* E-mail: eschadt@pacificbiosciences.com
Affiliations Department of Integrative and Systems Biology, Sage Bionetworks, Seattle, Washington, United States of America, Pacific Biosciences, Menlo Park, California, United States of America
Competing Interests
The senior author (EES) is the Chief Scientific Officer of Pacific Biosciences and owns stock in that company. A number of the other authors were employees of Merck when the work presented in this manuscript was carried out.
Author Contributions
Conceived and designed the experiments: HZ EES. Performed the experiments: DTW MPK. Analyzed the data: HZ EES. Contributed reagents/materials/analysis tools: JB PYL CM XY DJM BZ DG RD KH SW CFS SQ MRT CMK BSY VC ADA LMK. Wrote the paper: HZ EES.