About the Authors

Satoshi Kurosaka

Affiliation Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

N. Adrian Leu

Affiliation Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Fangliang Zhang

Affiliation Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Ralph Bunte

Affiliation University Laboratory Animal Resources, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Sougata Saha

Affiliation Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Junling Wang

Affiliation Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Caiying Guo

Affiliation Janelia Farm, Ashburn, Virginia, United States of America

Wei He

Affiliation Gene Targeting and Transgenic Facility, University of Connecticut Health Center, Farmington, Connecticut, United States of America

Anna Kashina

akashina@vet.upenn.edu

Affiliation Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SK NAL AK. Performed the experiments: SK NAL RB SS AK. Analyzed the data: SK NAL RB SS AK. Contributed reagents/materials/analysis tools: FZ JW CG WH. Wrote the paper: SK AK.