About the Authors

Sungho Won

Affiliations Department of Statistics, Chung-Ang University, Seoul, Korea, Research Center for Data Science, Chung-Ang University, Seoul, Korea

Jemma B. Wilk

Affiliation Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, United States of America

Rasika A. Mathias

Affiliation Genometrics Section, Inherited Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Baltimore, Maryland, United States of America

Christopher J. O'Donnell

Affiliations National Heart, Lung, and Blood Institute and Framingham Heart Study, Bethesda, Maryland, United States of America, Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Edwin K. Silverman

Affiliations Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

Kathleen Barnes

Affiliation Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America

George T. O'Connor

Affiliation Pulmonary Center, Boston University School of Medicine, Boston, Massachusetts, United States of America

Scott T. Weiss

Affiliations Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America, Center for Genomic Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

Christoph Lange

clange@hsph.harvard.edu

Affiliations Harvard Medical School, Boston, Massachusetts, United States of America, Center for Genomic Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SW CL. Performed the experiments: SW. Analyzed the data: SW JBW RM CJO EKS KB GTO STW. Contributed reagents/materials/analysis tools: SW. Wrote the paper: SW CL.