About the Authors

Shiguo Zhou

Affiliation Laboratory for Molecular and Computational Genomics, Department of Chemistry, Laboratory of Genetics, UW Biotechnology Center, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

Fusheng Wei

Affiliation Department of Plant Sciences, Arizona Genomics Institute, University of Arizona, Tucson, Arizona, United States of America

John Nguyen

Affiliation Departments of Mathematics, Biology, and Computer Science, University of Southern California, Los Angeles, California, United States of America

Mike Bechner

Affiliation Laboratory for Molecular and Computational Genomics, Department of Chemistry, Laboratory of Genetics, UW Biotechnology Center, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

Konstantinos Potamousis

Affiliation Laboratory for Molecular and Computational Genomics, Department of Chemistry, Laboratory of Genetics, UW Biotechnology Center, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

Steve Goldstein

Affiliation Laboratory for Molecular and Computational Genomics, Department of Chemistry, Laboratory of Genetics, UW Biotechnology Center, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

Louise Pape

Affiliation Laboratory for Molecular and Computational Genomics, Department of Chemistry, Laboratory of Genetics, UW Biotechnology Center, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

Michael R. Mehan

Affiliation Departments of Mathematics, Biology, and Computer Science, University of Southern California, Los Angeles, California, United States of America

Chris Churas

Affiliation Laboratory for Molecular and Computational Genomics, Department of Chemistry, Laboratory of Genetics, UW Biotechnology Center, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

Shiran Pasternak

Affiliation Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America

Dan K. Forrest

Affiliation Laboratory for Molecular and Computational Genomics, Department of Chemistry, Laboratory of Genetics, UW Biotechnology Center, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

Roger Wise

Affiliation Corn Insects and Crop Genetics Research, United States Department of Agriculture–Agricultural Research Service and Department of Plant Pathology, Iowa State University, Ames, Iowa, United States of America

Doreen Ware

Affiliations Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America, Plant, Soil, and Nutrition Research, United States Department of Agriculture–Agricultural Research Service, Ithaca, New York, United States of America

Rod A. Wing

Affiliation Department of Plant Sciences, Arizona Genomics Institute, University of Arizona, Tucson, Arizona, United States of America

Michael S. Waterman

Affiliation Departments of Mathematics, Biology, and Computer Science, University of Southern California, Los Angeles, California, United States of America

Miron Livny

Affiliation Computer Sciences Department, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

David C. Schwartz

dcschwartz@wisc.edu

Affiliation Laboratory for Molecular and Computational Genomics, Department of Chemistry, Laboratory of Genetics, UW Biotechnology Center, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SZ DCS. Performed the experiments: SZ MB KP. Analyzed the data: SZ FW JN SG LP DW RAW MSW DCS SP. Contributed reagents/materials/analysis tools: JN SG MRM CC DKF RW DW ML. Wrote the paper: SZ LP DCS.