About the Authors

Nancy L. Heard-Costa, Larry D. Atwood
Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, United States of America

M. Carola Zillikens, Karol Estrada, Fernando Rivadeneira, André G. Uitterlinden
Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands

Keri L. Monda, Kari E. North
Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

Åsa Johansson, Ulf Gyllensten
Department of Genetics and Pathology, Uppsala University, Uppsala, Sweden

Tamara B. Harris, Melissa Garcia, Lenore J. Launer
Laboratory of Epidemiology, Demography, and Biometry, Intramural Research Program, National Institute on Aging, Bethesda, Maryland, United States of America

Mao Fu, Braxton D. Mitchell, Patrick F. McArdle, Alan R. Shuldiner, Jeffrey R. O'Connell
Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

Talin Haritunians, Yii-Der Ida Chen, Jerome I. Rotter
Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America

Mary F. Feitosa, Xiaoyi Gao, Aldi Kraja, Michael A. Province, Qunyuan Zhang, Ingrid B. Borecki
Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America

Thor Aspelund, Gudny Eiriksdottir, Albert V. Smith, Vilmundur Gudnason
Heart Preventive Clinic and Research Institute, Icelandic Heart Association, Kopavogur, Iceland

Thor Aspelund, Vilmundur Gudnason
University of Iceland, Reykjavik, Iceland

Suzette J. Bielinski
Division of Epidemiology, Mayo Clinic, Rochester, Minnesota, United States of America

Eric Boerwinkle
Human Genetics Center and Institute of Molecular Medicine, University of Texas Health Science Center, Houston, Texas, United States of America

Fred Brancati
Department of Medicine and Epidemiology, Johns Hopkins University, Baltimore, Maryland, United States of America

Ellen W. Demerath, James S. Pankow
Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, United States of America

Alice M. Arnold, Barbara McKnight
Department of Biostatistics, University of Washington, Seattle, Washington, United States of America

Nicole L. Glazer
Department of Internal Medicine, University of Washington, Seattle, Washington, United States of America

Bruce M. Psaty
Department of Epidemiology, Medicine, & Health Services, University of Washington, Seattle, Washington, United States of America

Najaf Amin, Maksim Struchalin, Yurii S. Aulchenko, Albert Hofman, Fernando Rivadeneira, André G. Uitterlinden, Jacqueline C. M. Witteman, Cornelia M. van Duijn
Department of Epidemiology and Biostatistics, Erasmus University Medical Center, Rotterdam, The Netherlands

Harry Campbell, Igor Rudan
Department of Public Health Sciences, University of Edinburgh Medical School, Edinburgh, Scotland, United Kingdom

Cristian Pattaro, Peter P. Pramstaller
Institute of Genetic Medicine, European Academy Bozen/Bolzano,Bolzano, Italy

Peter P. Pramstaller
Department of Neurology, University of Lübeck, Lübeck, Germany

Peter P. Pramstaller
Department of Neurology, Central Regional Hospital, Bolzano, Italy

Igor Rudan
Croatian Centre for Global Health, University of Split Medical School, Split, Croatia

Igor Rudan
Institute for Clinical Medical Research, University Hospital “Sestre Milosrdnice,” Zagreb, Croatia

Veronique Vitart
Human Genetics Unit, Institute of Genetics and Molecular Medicine, Edinburgh, Scotland, United Kingdom

Josée Dupuis, Charles C. White, L. Adrienne Cupples
Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America

Joel N. Hirschhorn
Program in Genomics and Divisions of Endocrinology and Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

Cashell E. Jaquish
Division of Prevention and Population Sciences, National Heart, Lung, and Blood Institute, Bethesda, Maryland, United States of America

Christopher J. O'Donnell, Caroline S. Fox
Division of Intramural Research, National Heart, Lung and Blood Institute, Framingham Heart Study, Framingham, Massachusetts, United States of America

Ramachandran S. Vasan
Boston University School of Medicine, Boston, Massachusetts, United States of America

Ramachandran S. Vasan
The Framingham Heart Study, Framingham, Massachusetts, United States of America

Ben A. Oostra
Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands

Robert C. Kaplan
Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, United States of America

Caroline S. Fox
Division of Endocrinology, Metabolism, and Diabetes, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NLHC MCZ TBH MF GE MG LJL BDM ARS EB FB JSP BMP JIR HC UG PPP IR MAP LDA JNH CEJ CJO AH FR AGU JCMW BAO RCK VG JRO IBB CMvD LAC CSF KEN. Analyzed the data: NLHC KLM ÅJ MF MFF TA AVS BDM PFM NLG BM NA CP MS VV XG AK MAP QZ JD CJO CCW YSA KE FR AGU VG JRO IBB CMvD LAC. Contributed reagents/materials/analysis tools: TBH TH TA GE LJL AVS BDM ARS SJB EB NLG BMP JIR HC UG PPP IR FR AGU JCMW VG KEN. Wrote the paper: NLHC MCZ KLM ÅJ TBH MF TH MFF FB EWD JSP AMA YDIC NLG JIR CJO RSV BAO RCK VG JRO IBB CMvD LAC CSF KEN.