About the Authors

Maja Bucan, Vlad Kustanovich, Clara M. Lajonchere, Rita M. Cantor, Daniel H. Geschwind
Autism Genetic Resource Exchange, Autism Speaks, Los Angeles, California, United States of America

Maja Bucan, Kai Wang, Dexter Hadley, Nicole B. Gidaya, Ingrid Lindquist
Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Maja Bucan, Junhyong Kim
Penn Center for Bioinformatics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Brett S. Abrahams, Edward I. Herman, Lisa I. Sonnenblick, Daniel H. Geschwind
Department of Neurology, University of California Los Angeles, Los Angeles, California, United States of America

Kai Wang, Joseph T. Glessner, Marcin Imielinski, Jonathan P. Bradfield, Cecilia Kim, Struan F. A. Grant, Hakon Hakonarson
Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

Ana I. Alvarez Retuerto, Daniel H. Geschwind
Department of Psychiatry, University of California Los Angeles, Philadelphia, Pennsylvania, United States of America

Ana I. Alvarez Retuerto, Ted Hutman, Marian Sigman, Daniel H. Geschwind
Center for Autism Research, Semel Institute for Neuroscience and Behavior, University of California Los Angeles, Los Angeles, California, United States of America

Dexter Hadley, Junhyong Kim
Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Clara M. Lajonchere
Department of Biomedical Engineering, University of Southern California, Los Angeles, California, United States of America

Andrew Singleton
Porter Neuroscience Research Center, National Institute on Aging, National Institute of Health, Bethesda, Maryland, United States of America

Thomas H. Wassink
Department of Psychiatry, University of Iowa, Iowa City, Iowa, United States of America

William M. McMahon, Hilary Coon
Department of Psychiatry, University of Utah, Salt Lake City, Utah, United States of America

Thomas Owley, John A. Sweeney, Edwin H. Cook
Institute for Juvenile Research, Department of Psychiatry, University of Illinois at Chicago, Chicago, Illinois, United States of America

John I. Nurnberger Jr
Department of Psychiatry, Indiana University, Indianapolis, Indiana, United States of America

Mingyao Li
Department of Biostatistics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Rita M. Cantor, Daniel H. Geschwind
Department of Human Genetics, University of California Los Angeles, Los Angeles, California, United States of America

Nancy J. Minshew
Department of Psychiatry and Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

James S. Sutcliffe
Center for Molecular Neuroscience and Vanderbilt Kennedy Center, Vanderbilt University, Vanderbilt University, Nashville, Tennessee, United States of America

Geraldine Dawson
Department of Psychiatry, University of North Carolina, Chapel Hill, North Carolina, United States of America

Joseph D. Buxbaum
Seaver Autism Center for Research and Treatment, Departments of Psychiatry, Neuroscience, Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, New York

Struan F. A. Grant, Hakon Hakonarson
Department of Pediatrics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Gerard D. Schellenberg
Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MB BSA KW DHG HH. Performed the experiments: BSA LIS CK. Analyzed the data: MB BSA KW JTG EIH MI DH JPB NBG IL JK ML RMC SFAG. Contributed reagents/materials/analysis tools: AIAR TH MS VK CML AS THW WMM TO JAS HC JIN NJM JSS EHC GD JDB GDS. Wrote the paper: MB BSA KW SFAG DHG HH.