About the Authors

Sreekumar G. Pillai

sreekumar.g.pillai@gsk.com (SGP); d.goldstein@duke.edu (DBG)

Affiliation Genetics Division, GlaxoSmithKline Research and Development, Research Triangle Park, North Carolina, United States of America

Dongliang Ge

Contributed equally to this work with: Dongliang Ge, Guohua Zhu, Xiangyang Kong

Affiliation IGSP Center for Population Genomics and Pharmacogenetics, Duke University, Durham, North Carolina, United States of America

Guohua Zhu

Contributed equally to this work with: Dongliang Ge, Guohua Zhu, Xiangyang Kong

Affiliation Genetics Division, GlaxoSmithKline Research and Development, Research Triangle Park, North Carolina, United States of America

Xiangyang Kong

Contributed equally to this work with: Dongliang Ge, Guohua Zhu, Xiangyang Kong

Affiliation Genetics Division, GlaxoSmithKline Research and Development, Research Triangle Park, North Carolina, United States of America

Kevin V. Shianna

Affiliation IGSP Center for Population Genomics and Pharmacogenetics, Duke University, Durham, North Carolina, United States of America

Anna C. Need

Affiliation IGSP Center for Population Genomics and Pharmacogenetics, Duke University, Durham, North Carolina, United States of America

Sheng Feng

Affiliation IGSP Center for Population Genomics and Pharmacogenetics, Duke University, Durham, North Carolina, United States of America

Craig P. Hersh

Affiliation Brigham and Women's Hospital, Boston, Massachusetts, United States of America

Per Bakke

Affiliation University of Bergen, Bergen, Norway

Amund Gulsvik

Affiliation University of Bergen, Bergen, Norway

Andreas Ruppert

Affiliation Genetics Research Centre, Munich, Germany

Karin C. Lødrup Carlsen

Affiliation Ullevaal University Hospital and the Faculty of Medicine, University of Oslo, Oslo, Norway

Allen Roses

Affiliations IGSP Center for Population Genomics and Pharmacogenetics, Duke University, Durham, North Carolina, United States of America, Deane Drug Discovery Institute, Duke University, Durham, North Carolina, United States of America

Wayne Anderson

Affiliation Genetics Division, GlaxoSmithKline Research and Development, Research Triangle Park, North Carolina, United States of America

ICGN Investigators
Stephen I. Rennard

Affiliation Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska, United States of America

David A. Lomas

Affiliation Cambridge Institute for Medical Research, Cambridge, United Kingdom

Edwin K. Silverman

Affiliation Brigham and Women's Hospital, Boston, Massachusetts, United States of America

David B. Goldstein

sreekumar.g.pillai@gsk.com (SGP); d.goldstein@duke.edu (DBG)

Affiliation IGSP Center for Population Genomics and Pharmacogenetics, Duke University, Durham, North Carolina, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SGP PB AG KCLC AR WA SIR DAL EKS DBG. Performed the experiments: KVS ACN AR KCLC. Analyzed the data: DG GZ XK SF CPH. Wrote the paper: SGP EKS DBG.