About the Authors

Russell Bell

Contributed equally to this work with: Russell Bell, Alan Hubbard, Rakesh Chettier

Affiliation Prolexys Pharmaceuticals, Salt Lake City, Utah, United States of America

Alan Hubbard

Contributed equally to this work with: Russell Bell, Alan Hubbard, Rakesh Chettier

Affiliations School of Public Health, University of California Berkeley, Berkeley, California, United States of America, Buck Institute for Age Research, Novato, California, United States of America

Rakesh Chettier

Contributed equally to this work with: Russell Bell, Alan Hubbard, Rakesh Chettier

Affiliation Prolexys Pharmaceuticals, Salt Lake City, Utah, United States of America

Di Chen

Affiliation Buck Institute for Age Research, Novato, California, United States of America

John P. Miller

Affiliation Buck Institute for Age Research, Novato, California, United States of America

Pankaj Kapahi

Affiliation Buck Institute for Age Research, Novato, California, United States of America

Mark Tarnopolsky

Affiliation McMaster University Medical Center, Hamilton, Ontario, Canada

Sudhir Sahasrabuhde

Affiliation Prolexys Pharmaceuticals, Salt Lake City, Utah, United States of America

Simon Melov

Affiliation Buck Institute for Age Research, Novato, California, United States of America

Robert E. Hughes

rhughes@buckinstitute.org

Affiliation Buck Institute for Age Research, Novato, California, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RB AH RC DC SM REH. Performed the experiments: DC MT. Analyzed the data: RB AH RC DC JPM SM REH. Contributed reagents/materials/analysis tools: DC PK MT SS SM. Wrote the paper: JPM REH.