About the Authors

Natalie D. Fedorova

Affiliation The J. Craig Venter Institute, Rockville, Maryland, United States of America

Nora Khaldi

Affiliation Department of Genetics, Smurfit Institute, University of Dublin, Trinity College, Dublin, Ireland

Vinita S. Joardar

Affiliation The J. Craig Venter Institute, Rockville, Maryland, United States of America

Rama Maiti

Affiliation The J. Craig Venter Institute, Rockville, Maryland, United States of America

Paolo Amedeo

Affiliation The J. Craig Venter Institute, Rockville, Maryland, United States of America

Michael J. Anderson

Affiliation School of Medicine and Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom

Jonathan Crabtree

Affiliation The J. Craig Venter Institute, Rockville, Maryland, United States of America

Joana C. Silva

Affiliation The J. Craig Venter Institute, Rockville, Maryland, United States of America

Jonathan H. Badger

Affiliation The J. Craig Venter Institute, Rockville, Maryland, United States of America

Ahmed Albarraq

Affiliation School of Medicine and Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom

Sam Angiuoli

Affiliation The J. Craig Venter Institute, Rockville, Maryland, United States of America

Howard Bussey

Affiliation Department of Biology, McGill University, Montreal, Quebec, Canada

Paul Bowyer

Affiliation School of Medicine and Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom

Peter J. Cotty

Affiliation Agricultural Research Service, United States Department of Agriculture, Department of Plant Sciences, University of Arizona, Tucson, Arizona, United States of America

Paul S. Dyer

Affiliation School of Biology, University of Nottingham, Nottingham, United Kingdom

Amy Egan

Affiliation The J. Craig Venter Institute, Rockville, Maryland, United States of America

Kevin Galens

Affiliation The J. Craig Venter Institute, Rockville, Maryland, United States of America

Claire M. Fraser-Liggett

Affiliation The J. Craig Venter Institute, Rockville, Maryland, United States of America

Brian J. Haas

Affiliation The J. Craig Venter Institute, Rockville, Maryland, United States of America

Jason M. Inman

Affiliation The J. Craig Venter Institute, Rockville, Maryland, United States of America

Richard Kent

Affiliation School of Medicine and Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom

Sebastien Lemieux

Affiliation Institute for Research in Immunology and Cancer, Department of Computer Science and Operations Research, Universite de Montreal, Montreal, Canada

Iran Malavazi

Affiliation Departamento de Ciencias Farmaceuticas, Faculdade de Ciencias Farmaceuticas de Ribeirao Preto, Universidade de Sao Paulo, Sao Paulo, Brazil

Joshua Orvis

Affiliation The J. Craig Venter Institute, Rockville, Maryland, United States of America

Terry Roemer

Affiliation Merck & Co., Inc., Whitehouse Station, New Jersey, United States of America

Catherine M. Ronning

Affiliation The J. Craig Venter Institute, Rockville, Maryland, United States of America

Jaideep P. Sundaram

Affiliation The J. Craig Venter Institute, Rockville, Maryland, United States of America

Granger Sutton

Affiliation The J. Craig Venter Institute, Rockville, Maryland, United States of America

Geoff Turner

Affiliation Department of Molecular Biology and Biotechnology, The University of Sheffield, Sheffield, United Kingdom

J. Craig Venter

Affiliation The J. Craig Venter Institute, Rockville, Maryland, United States of America

Owen R. White

Affiliation The J. Craig Venter Institute, Rockville, Maryland, United States of America

Brett R. Whitty

Affiliation The J. Craig Venter Institute, Rockville, Maryland, United States of America

Phil Youngman

Affiliation Merck & Co., Inc., Whitehouse Station, New Jersey, United States of America

Kenneth H. Wolfe

Affiliation Department of Genetics, Smurfit Institute, University of Dublin, Trinity College, Dublin, Ireland

Gustavo H. Goldman

Affiliation Departamento de Ciencias Farmaceuticas, Faculdade de Ciencias Farmaceuticas de Ribeirao Preto, Universidade de Sao Paulo, Sao Paulo, Brazil

Jennifer R. Wortman

Affiliation The J. Craig Venter Institute, Rockville, Maryland, United States of America

Bo Jiang

Affiliation Merck & Co., Inc., Whitehouse Station, New Jersey, United States of America

David W. Denning

Affiliation School of Medicine and Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom

William C. Nierman

wnierman@jcvi.org

Affiliations The J. Craig Venter Institute, Rockville, Maryland, United States of America, Department of Biochemistry and Molecular Biology, The George Washington University School of Medicine, Washington DC, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DD WN. Performed the experiments: MA AA HB PC RK IM. Analyzed the data: NF NK VJ RM PA MA JC JS JB SA PB PC PD AE KG BH JI SL JO TR CR JS GS GT BW PY KW GG JW BJ DD. Contributed reagents/materials/analysis tools: JC JS JB SA AE CF BH JO GS JV OW. Wrote the paper: NF NK DD WN.