About the Authors

Rahul C Deo

To whom correspondence should be addressed. E-mail: rdeo@partners.org (RCD); reich@genetics.med.harvard.edu (DR)

Affiliations Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America , Cardiology Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Nick Patterson

Affiliation Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Boston, Massachusetts, United States of America

Arti Tandon

Affiliations Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America , Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Boston, Massachusetts, United States of America

Gavin J McDonald

Affiliations Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America , Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Boston, Massachusetts, United States of America

Christopher A Haiman

Affiliation Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America

Kristin Ardlie

Affiliations Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Boston, Massachusetts, United States of America , Genomics Collaborative, Cambridge, Massachusetts, United States of America

Brian E Henderson

Affiliation Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America

Sean O Henderson

Affiliations Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America , Department of Emergency Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America

David Reich

To whom correspondence should be addressed. E-mail: rdeo@partners.org (RCD); reich@genetics.med.harvard.edu (DR)

Affiliations Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America , Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Boston, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

RCD, SOH, and DR conceived and designed the experiments. RCD and GJM performed the experiments. RCD, NP, AT, and DR analyzed the data. RCD, NP, AT, CAH, KA, BEH, SOH, and DR contributed reagents/materials/analysis tools. RCD and DR wrote the paper.