About the Authors

Andrea M Santangelo

Contributed equally to this work with: Andrea M Santangelo, Flávio S. J de Souza, Lucía F Franchini

Affiliation Instituto de Investigaciones en Ingeniería Genética y Biología Molecular, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina

Flávio S. J de Souza

Contributed equally to this work with: Andrea M Santangelo, Flávio S. J de Souza, Lucía F Franchini

Affiliation Instituto de Investigaciones en Ingeniería Genética y Biología Molecular, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina

Lucía F Franchini

Contributed equally to this work with: Andrea M Santangelo, Flávio S. J de Souza, Lucía F Franchini

Affiliation Instituto de Investigaciones en Ingeniería Genética y Biología Molecular, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina

Viviana F Bumaschny

Affiliation Instituto de Investigaciones en Ingeniería Genética y Biología Molecular, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina

Malcolm J Low

Affiliations Center for the Study of Weight Regulation and Associated Disorders, Portland, Oregon, United States of America , Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, Oregon, United States of America

Marcelo Rubinstein

To whom correspondence should be addressed. E-mail: mrubins@dna.uba.ar

Affiliations Instituto de Investigaciones en Ingeniería Genética y Biología Molecular, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina , Center for the Study of Weight Regulation and Associated Disorders, Portland, Oregon, United States of America , Departmento de Fisiología, Biología Molecular y Celular, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina , Centro de Estudios Científicos, Valdivia, Chile

Competing Interests

FSJdS, MJL, and MR have intellectual property and patent interests in the POMC neuronal-specific enhancers and have received income from the licensing of this intellectual property and related research material to financially interested companies.

Author Contributions

AMS, FSJdS, LFF, MJL, and MR conceived and designed the experiments and analyzed the data. AMS, FSJdS, LFF, and VFB performed the experiments. LFF, MJL, and MR contributed reagents/materials/analysis tools. FSJdS, LFF, and MR wrote the paper. MJL revised the manuscript.