X Chromosome Reactivation Initiates in Nascent Primordial Germ Cells in Mice

Open Access

Peer-reviewed

Research Article

Michihiko Sugimoto,

Affiliation Technology and Development Team for Mammalian Cellular Dynamics, BioResource Center, RIKEN Tsukuba Institute, Tsukuba, Ibaraki, Japan
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Kuniya Abe

*To whom correspondence should be addressed. E-mail: abe@rtc.riken.jp

Affiliation Technology and Development Team for Mammalian Cellular Dynamics, BioResource Center, RIKEN Tsukuba Institute, Tsukuba, Ibaraki, Japan
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About the Authors

Michihiko Sugimoto

Affiliation Technology and Development Team for Mammalian Cellular Dynamics, BioResource Center, RIKEN Tsukuba Institute, Tsukuba, Ibaraki, Japan

Kuniya Abe

*To whom correspondence should be addressed. E-mail: abe@rtc.riken.jp

Affiliation Technology and Development Team for Mammalian Cellular Dynamics, BioResource Center, RIKEN Tsukuba Institute, Tsukuba, Ibaraki, Japan

The authors have declared that no competing interests exist.

MS and KA conceived and designed the experiments and wrote the paper. MS performed the experiments and analyzed the data.

X chromosome inactivation
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X-linked traits
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Germ cells
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DNA methylation
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X chromosomes
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Gene expression
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Epigenetics
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Embryos
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