About the Authors

Chin-Yo Lin

Contributed equally to this work with: Chin-Yo Lin, Vinsensius B Vega

Address ¤ Current address: Department of Microbiology and Molecular Biology, Brigham Young University, Provo, Utah, United States of America

Affiliation Genome Institute of Singapore, Singapore, Republic of Singapore

Vinsensius B Vega

Contributed equally to this work with: Chin-Yo Lin, Vinsensius B Vega

Affiliation Genome Institute of Singapore, Singapore, Republic of Singapore

Jane S Thomsen

Affiliation Genome Institute of Singapore, Singapore, Republic of Singapore

Tao Zhang

Affiliation Genome Institute of Singapore, Singapore, Republic of Singapore

Say Li Kong

Affiliation Genome Institute of Singapore, Singapore, Republic of Singapore

Min Xie

Affiliation Genome Institute of Singapore, Singapore, Republic of Singapore

Kuo Ping Chiu

Affiliation Genome Institute of Singapore, Singapore, Republic of Singapore

Leonard Lipovich

Affiliation Genome Institute of Singapore, Singapore, Republic of Singapore

Daniel H Barnett

Affiliation Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America

Fabio Stossi

Affiliation Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America

Ailing Yeo

Affiliation Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Republic of Singapore

Joshy George

Affiliation Genome Institute of Singapore, Singapore, Republic of Singapore

Vladimir A Kuznetsov

Affiliation Genome Institute of Singapore, Singapore, Republic of Singapore

Yew Kok Lee

Affiliation Genome Institute of Singapore, Singapore, Republic of Singapore

Tze Howe Charn

Affiliation Genome Institute of Singapore, Singapore, Republic of Singapore

Nallasivam Palanisamy

Affiliation Genome Institute of Singapore, Singapore, Republic of Singapore

Lance D Miller

Affiliation Genome Institute of Singapore, Singapore, Republic of Singapore

Edwin Cheung

Affiliations Genome Institute of Singapore, Singapore, Republic of Singapore , Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Republic of Singapore

Benita S Katzenellenbogen

Affiliation Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America

Yijun Ruan

Affiliation Genome Institute of Singapore, Singapore, Republic of Singapore

Guillaume Bourque

Affiliation Genome Institute of Singapore, Singapore, Republic of Singapore

Chia-Lin Wei

Affiliation Genome Institute of Singapore, Singapore, Republic of Singapore

Edison T Liu

To whom correspondence should be addressed. E-mail: liue@gis.a-star.edu.sg

Affiliation Genome Institute of Singapore, Singapore, Republic of Singapore

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

CYL, VBV, BSK, YR, and ETL conceived and designed the experiments. CYL, JST, TZ, SLK, MX, DHB, FS, AY, YKL, NP, LDM, EC, YR, and CLW performed the experiments. CYL, VBV, JST, KPC, LL, FS, JG, VAK, THC, LDM, EC, BSK, GB, CLW, and ETL analyzed the data. VBV, JST, DHB, FS, VAK, NP, LDM, EC, YR, GB, and CLW contributed reagents/materials/analysis tools. CYL, VBV, JST, BSK, GB, and ETL wrote the paper.