About the Authors

Michael B Stadler

To whom correspondence should be addressed. E-mail: michael.stadler@fmi.ch (MBS); cburge@mit.edu (CBB)

Address ¤ Current address: Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland

Affiliation Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Noam Shomron

Affiliation Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Gene W Yeo

Affiliation Crick-Jacobs Center for Computational and Theoretical Biology and Laboratory of Genetics, The Salk Institute, La Jolla, California, United States of America

Aniket Schneider

Affiliation Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Xinshu Xiao

Affiliation Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Christopher B Burge

To whom correspondence should be addressed. E-mail: michael.stadler@fmi.ch (MBS); cburge@mit.edu (CBB)

Affiliation Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

MBS, NS, GWY, and CBB conceived and designed the experiments. MBS, NS, and AS performed the experiments. MBS analyzed the data. MBS and XX contributed reagents/materials/analysis tools. MBS and CBB wrote the paper.