About the Authors

Chris C. A Spencer

Contributed equally to this work with: Chris C. A Spencer, Panos Deloukas

Affiliation Department of Statistics, University of Oxford, Oxford, United Kingdom

Panos Deloukas

Contributed equally to this work with: Chris C. A Spencer, Panos Deloukas

Affiliation Wellcome Trust Sanger Institute, Hinxton, United Kingdom

Sarah Hunt

Affiliation Wellcome Trust Sanger Institute, Hinxton, United Kingdom

Jim Mullikin

Affiliation National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America

Simon Myers

Affiliations Department of Statistics, University of Oxford, Oxford, United Kingdom , Broad Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Bernard Silverman

Affiliation Department of Statistics, University of Oxford, Oxford, United Kingdom

Peter Donnelly

Affiliation Department of Statistics, University of Oxford, Oxford, United Kingdom

David Bentley

Affiliation Solexa Ltd, Little Chesterford, United Kingdom

Gil McVean

To whom correspondence should be addressed. E-mail: mcvean@stats.ox.ac.uk

Affiliation Department of Statistics, University of Oxford, Oxford, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

SM, P. Donnelly, DB, and GM conceived and designed the experiments. P. Deloukas, SH, and JM performed the experiments. CCAS, JM, SM, and GM analyzed the data. P. Deloukas, SH, BS, and DB contributed reagents/materials/analysis tools. DB and GM jointly supervised the project. CCAS and GM wrote the paper.