About the Authors

Robert Clarke

Contributed equally to this work with: Robert Clarke, Peng Xu

To whom correspondence should be addressed. E-mail: robert.clarke@ctsu.ox.ac.uk

Affiliation Clinical Trial Service Unit, Old Road Campus, Oxford, United Kingdom

Peng Xu

Contributed equally to this work with: Robert Clarke, Peng Xu

Affiliation Centre National de Genotypage, Paris, France

Derrick Bennett

Affiliation Clinical Trial Service Unit, Old Road Campus, Oxford, United Kingdom

Sarah Lewington

Affiliation Clinical Trial Service Unit, Old Road Campus, Oxford, United Kingdom

Krina Zondervan

Affiliation Wellcome Trust Centre for Human Genetics, Old Road Campus, Oxford, United Kingdom

Sarah Parish

Affiliation Clinical Trial Service Unit, Old Road Campus, Oxford, United Kingdom

Alison Palmer

Affiliation Clinical Trial Service Unit, Old Road Campus, Oxford, United Kingdom

Sarah Clark

Affiliation Clinical Trial Service Unit, Old Road Campus, Oxford, United Kingdom

Lon Cardon

Affiliation Wellcome Trust Centre for Human Genetics, Old Road Campus, Oxford, United Kingdom

Richard Peto

Affiliation Clinical Trial Service Unit, Old Road Campus, Oxford, United Kingdom

Mark Lathrop

Affiliation Centre National de Genotypage, Paris, France

Rory Collins

Affiliation Clinical Trial Service Unit, Old Road Campus, Oxford, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

R. Clarke, P. Xu, D. Bennett, S. Parish, R. Peto, M. Lathrop, and R. Collins conceived and designed the experiments. R. Clarke, P. Xu, D. Bennett, S. Clark, M. Lathrop, and R. Collins performed the experiments. R. Clarke, P. Xu, D. Bennett, S. Lewington, K. Zondervan, S. Parish, A. Palmer, L. Cardon, M. Lathrop, and R. Collins analyzed the data. R. Clarke, P. Xu, R. Peto, M. Lathrop, and R. Collins contributed reagents/materials/analysis tools. R. Clarke, P. Xu, D. Bennett, S. Lewington, K. Zondervan, S. Parish, A. Palmer, L. Cardon, R. Peto, M. Lathrop, and R. Collins wrote the paper.