About the Authors

Kevin Pruitt

Affiliation The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States of America

Rebekah L Zinn

Affiliations The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States of America , The Graduate Program in Cellular and Molecular Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Joyce E Ohm

Affiliation The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States of America

Kelly M McGarvey

Affiliations The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States of America , The Graduate Program in Cellular and Molecular Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Sung-Hae L Kang

Affiliation The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States of America

D. Neil Watkins

Affiliation The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States of America

James G Herman

Affiliation The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States of America

Stephen B Baylin

To whom correspondence should be addressed. E-mail: sbaylin@jhmi.edu

Affiliation The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States of America

Competing Interests

SBB is a consultant to OncoMethylome Sciences. Under licensing agreement between the Johns Hopkins University and this company, MSP was licensed to OncoMethylome Sciences, and they are entitled to a share of the royalties received by the university from sales of the licensed technology.

Author Contributions

KP and SBB conceived and designed the experiments. KP, RLZ, JEO, KMM, and SHLK performed the experiments. KP, RLZ, KMM, DNW, JGH, and SBB analyzed the data. KP, JGH, and SBB contributed reagents/materials and wrote the paper.