About the Authors

Xu-Gang Xia, Hongxia Zhou, Zuoshang Xu
Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

Enrique Samper, Simon Melov
Buck Institute for Age Research, Novato, California, United States of America

Zuoshang Xu
Cell Biology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

Zuoshang Xu
Neuroscience Program, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

Corresponding Author

zuoshang.xu@umassmed.edu

Competing Interests

XGX, HZ, and ZX are authors of a pending patent on the Pol II–shRNA construct used in this study.

Author Contributions

XGX, HZ, and ZX conceived and designed the experiments. XGX, HZ, ES, and SM performed the experiments. XGX, HZ, ES, SM, and ZX analyzed the data. XGX, HZ, ES, and SM contributed reagents/materials/analysis tools. ZX wrote the paper.