Evolution after Introduction of a Novel Metabolic Pathway Consistently Leads to Restoration of Wild-Type Physiology

Sean Michael Carroll; Christopher J. Marx

doi:10.1371/journal.pgen.1003427

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Open Access

Peer-reviewed

Research Article

Evolution after Introduction of a Novel Metabolic Pathway Consistently Leads to Restoration of Wild-Type Physiology

Sean Michael Carroll,

Affiliation Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, United States of America
⨯
Christopher J. Marx

* E-mail: cmarx@oeb.harvard.edu

Affiliations Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, United States of America, Faculty of Arts and Sciences Center for Systems Biology, Harvard University, Cambridge, Massachusetts, United States of America
⨯

Evolution after Introduction of a Novel Metabolic Pathway Consistently Leads to Restoration of Wild-Type Physiology

Sean Michael Carroll,
Christopher J. Marx

Published: April 4, 2013
https://doi.org/10.1371/journal.pgen.1003427

About the Authors

Sean Michael Carroll

Affiliation Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, United States of America

Christopher J. Marx

* E-mail: cmarx@oeb.harvard.edu

Affiliations Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, United States of America, Faculty of Arts and Sciences Center for Systems Biology, Harvard University, Cambridge, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SMC CJM. Performed the experiments: SMC. Analyzed the data: SMC CJM. Contributed reagents/materials/analysis tools: SMC. Wrote the paper: SMC CJM.

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Gene expression
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