About the Authors

Sander G. Basten

Affiliation Department of Medical Oncology, University Medical Center Utrecht, Utrecht, The Netherlands

Erica E. Davis

Contributed equally to this work with: Erica E. Davis, Ad J. M. Gillis

Affiliation Center for Human Disease Modeling, Department of Pediatrics, and Department of Cell Biology, Duke University Medical Center, Durham, North Carolina, United States of America

Ad J. M. Gillis

Contributed equally to this work with: Erica E. Davis, Ad J. M. Gillis

Affiliation Department of Pathology, Erasmus MC, University Medical Center Rotterdam, Daniel den Hoed Cancer Center, Josephine Nefkens Institute, Rotterdam, The Netherlands

Ellen van Rooijen

Affiliations Department of Medical Oncology, University Medical Center Utrecht, Utrecht, The Netherlands, Hubrecht Institute, KNAW and University Medical Center Utrecht, Utrecht, The Netherlands

Hans Stoop

Affiliation Department of Pathology, Erasmus MC, University Medical Center Rotterdam, Daniel den Hoed Cancer Center, Josephine Nefkens Institute, Rotterdam, The Netherlands

Nikolina Babala

Affiliation Department of Medical Oncology, University Medical Center Utrecht, Utrecht, The Netherlands

Ive Logister

Affiliations Department of Medical Oncology, University Medical Center Utrecht, Utrecht, The Netherlands, Hubrecht Institute, KNAW and University Medical Center Utrecht, Utrecht, The Netherlands

Zachary G. Heath

Affiliation Center for Human Disease Modeling, Department of Pediatrics, and Department of Cell Biology, Duke University Medical Center, Durham, North Carolina, United States of America

Trudy N. Jonges

Affiliation Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands

Nicholas Katsanis

Affiliation Center for Human Disease Modeling, Department of Pediatrics, and Department of Cell Biology, Duke University Medical Center, Durham, North Carolina, United States of America

Emile E. Voest

Affiliation Department of Medical Oncology, University Medical Center Utrecht, Utrecht, The Netherlands

Freek J. van Eeden

Affiliation Hubrecht Institute, KNAW and University Medical Center Utrecht, Utrecht, The Netherlands

Rene H. Medema

Affiliation Department of Medical Oncology, University Medical Center Utrecht, Utrecht, The Netherlands

René F. Ketting

Affiliation Hubrecht Institute, KNAW and University Medical Center Utrecht, Utrecht, The Netherlands

Stefan Schulte-Merker

Affiliation Hubrecht Institute, KNAW and University Medical Center Utrecht, Utrecht, The Netherlands

Leendert H. J. Looijenga

Affiliation Hubrecht Institute, KNAW and University Medical Center Utrecht, Utrecht, The Netherlands

Rachel H. Giles

r.giles@umcutrecht.nl

Affiliations Department of Medical Oncology, University Medical Center Utrecht, Utrecht, The Netherlands, Department of Nephrology and Hypertension, University Medical Center Utrecht, Utrecht, The Netherlands

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SGB EvR EED NK EEV FJvE RHM RFK SS-M LHJL RHG. Performed the experiments: SGB EED AJMG HS IL NB ZGH RHG. Analyzed the data: SGB EED NB IL LHJL RHG. Contributed reagents/materials/analysis tools: TNJ. Wrote the paper: SGB EED LHJL RHG.