About the Authors

Derek M. van Pel

Affiliations Michael Smith Laboratories, University of British Columbia, Vancouver, Canada, Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, Canada

Irene J. Barrett

Affiliation Michael Smith Laboratories, University of British Columbia, Vancouver, Canada

Yoko Shimizu

Affiliation Department of Screening, Centre for Drug Research and Development, Vancouver, Canada

Babu V. Sajesh

Affiliation Department of Screening, Centre for Drug Research and Development, Vancouver, Canada

Brent J. Guppy

Affiliation Department of Screening, Centre for Drug Research and Development, Vancouver, Canada

Tom Pfeifer

Affiliation Department of Screening, Centre for Drug Research and Development, Vancouver, Canada

Kirk J. McManus

Affiliation Manitoba Institute of Cell Biology, Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Canada

Philip Hieter

hieter@msl.ubc.ca

Affiliation Michael Smith Laboratories, University of British Columbia, Vancouver, Canada

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DMvP IJB YS BVS BJG TP KJM PH. Performed the experiments: DMvP IJB YS BVS BJG KJM. Analyzed the data: DMvP IJB YS BVS BJG TP KJM PH. Contributed reagents/materials/analysis tools: DMvP TP KJM PH. Wrote the paper: DMvP IJB BVS BJG TP KJM PH.