About the Authors

Alexandra C. Nica

Affiliations Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom, Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland

Leopold Parts

Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom

Daniel Glass

Affiliation Department of Twin Research, King's College London, London, United Kingdom

James Nisbet

Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom

Amy Barrett

Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

Magdalena Sekowska

Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom

Mary Travers

Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

Simon Potter

Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom

Elin Grundberg

Affiliations Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom, Department of Twin Research, King's College London, London, United Kingdom

Kerrin Small

Affiliations Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom, Department of Twin Research, King's College London, London, United Kingdom

Åsa K. Hedman

Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

Veronique Bataille

Affiliation Department of Twin Research, King's College London, London, United Kingdom

Jordana Tzenova Bell

Affiliations Department of Twin Research, King's College London, London, United Kingdom, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

Gabriela Surdulescu

Affiliation Department of Twin Research, King's College London, London, United Kingdom

Antigone S. Dimas

Affiliations Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

Catherine Ingle

Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom

Frank O. Nestle

Affiliation St. John's Institute of Dermatology, King's College London, London, United Kingdom

Paola di Meglio

Affiliation St. John's Institute of Dermatology, King's College London, London, United Kingdom

Josine L. Min

Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

Alicja Wilk

Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom

Christopher J. Hammond

Affiliation Department of Twin Research, King's College London, London, United Kingdom

Neelam Hassanali

Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

Tsun-Po Yang

Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom

Stephen B. Montgomery

Affiliation Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland

Steve O'Rahilly

Affiliation University of Cambridge Metabolic Research Labs, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom

Cecilia M. Lindgren

Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

Krina T. Zondervan

Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

Nicole Soranzo

Affiliations Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom, Department of Twin Research, King's College London, London, United Kingdom

Inês Barroso

Affiliations Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom, University of Cambridge Metabolic Research Labs, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom

Richard Durbin

Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom

Kourosh Ahmadi

Affiliation Department of Twin Research, King's College London, London, United Kingdom

Panos Deloukas

emmanouil.dermitzakis@unige.ch (ETD); tim.spector@kcl.ac.uk (TDS); mark.mccarthy@drl.ox.ac.uk (MIM); panos@sanger.ac.uk (PD)

Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom

Mark I. McCarthy

emmanouil.dermitzakis@unige.ch (ETD); tim.spector@kcl.ac.uk (TDS); mark.mccarthy@drl.ox.ac.uk (MIM); panos@sanger.ac.uk (PD)

Affiliations Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, Oxford Centre for Diabetes, Endocrinology, and Metabolism, University of Oxford, Churchill Hospital, Oxford, United Kingdom, Oxford NIHR Biomedical Research Centre, Churchill Hospital, Oxford, United Kingdom

Emmanouil T. Dermitzakis

emmanouil.dermitzakis@unige.ch (ETD); tim.spector@kcl.ac.uk (TDS); mark.mccarthy@drl.ox.ac.uk (MIM); panos@sanger.ac.uk (PD)

Affiliation Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland

Timothy D. Spector

emmanouil.dermitzakis@unige.ch (ETD); tim.spector@kcl.ac.uk (TDS); mark.mccarthy@drl.ox.ac.uk (MIM); panos@sanger.ac.uk (PD)

Affiliation Department of Twin Research, King's College London, London, United Kingdom

The MuTHER Consortium

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SO KTZ RD KA PD MIM ETD TDS. Performed the experiments: DG JN AB MS MT CI. Analyzed the data: ACN LP. Contributed reagents/materials/analysis tools: EG KS ÅKH ASD TPY JLM SBM SP VB JTB GS FON PdM AW CJH NH CML NS IB. Wrote the paper: ACN ETD.