About the Authors

Ellen M. Wijsman

wijsman@u.washington.edu

Affiliations Division of Medical Genetics, University of Washington, Seattle, Washington, United States of America, Department of Biostatistics, University of Washington, Seattle, Washington, United States of America

Nathan D. Pankratz

Affiliation Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

Yoonha Choi

Affiliation Department of Biostatistics, University of Washington, Seattle, Washington, United States of America

Joseph H. Rothstein

Affiliation Division of Medical Genetics, University of Washington, Seattle, Washington, United States of America

Kelley M. Faber

Affiliation Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

Rong Cheng

Affiliation The Gertrude H. Sergievsky Center, The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University College of Physicians and Surgeons, New York, New York, United States of America

Joseph H. Lee

Affiliation The Gertrude H. Sergievsky Center, The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University College of Physicians and Surgeons, New York, New York, United States of America

Thomas D. Bird

Affiliations Division of Medical Genetics, University of Washington, Seattle, Washington, United States of America, Geriatric Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle Division, Seattle, Washington, United States of America, Department of Neurology, University of Washington, Seattle, Washington, United States of America

David A. Bennett

Affiliation Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States of America

Ramon Diaz-Arrastia

Affiliation Department of Neurology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

Alison M. Goate

Affiliation Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, United States of America

Martin Farlow

Affiliation Department of Neurology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

Bernardino Ghetti

Affiliation Department of Pathology, Division of Neuropathology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

Robert A. Sweet

Affiliation Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

Tatiana M. Foroud

Affiliation Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

Richard Mayeux

Affiliation The Gertrude H. Sergievsky Center, The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University College of Physicians and Surgeons, New York, New York, United States of America

The NIA-LOAD/NCRAD Family Study Group

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: EMW NDP JHL TMF RM. Analyzed the data: EMW NDP YC JHR KMF RC JHL. Contributed reagents/materials/analysis tools: TDB DAB RDA AMG MF BG RAS TMF RM. Wrote the paper: EMW NDP YC JHR JHL TDB DAB RDA AMG MF RAS TMF RM. Managed the data: KMF.