About the Authors

Weihua Zeng

Affiliation Department of Biological Chemistry, School of Medicine, University of California, Irvine, California, United States of America

Jessica C. de Greef

Affiliation Leiden University Medical Center, Center for Human and Clinical Genetics, Leiden, The Netherlands

Yen-Yun Chen

Affiliation Department of Biological Chemistry, School of Medicine, University of California, Irvine, California, United States of America

Richard Chien

Affiliation Department of Biological Chemistry, School of Medicine, University of California, Irvine, California, United States of America

Xiangduo Kong

Affiliation Department of Biological Chemistry, School of Medicine, University of California, Irvine, California, United States of America

Heather C. Gregson

Current address: Focus Diagnostics, Cypress, California, United States of America

Affiliation Department of Biological Chemistry, School of Medicine, University of California, Irvine, California, United States of America

Sara T. Winokur

Affiliation Department of Biological Chemistry, School of Medicine, University of California, Irvine, California, United States of America

April Pyle

Affiliation Institute for Stem Cell Biology and Medicine, Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine, University of California, Los Angeles, California, United States of America

Keith D. Robertson

Affiliation Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, Florida, United States of America

John A. Schmiesing

Affiliation Department of Biological Chemistry, School of Medicine, University of California, Irvine, California, United States of America

Virginia E. Kimonis

Affiliation Division of Medical Genetics and Metabolism, Department of Pediatrics, University of California Irvine Medical Center, Orange, California, United States of America

Judit Balog

Affiliation Leiden University Medical Center, Center for Human and Clinical Genetics, Leiden, The Netherlands

Rune R. Frants

Affiliation Leiden University Medical Center, Center for Human and Clinical Genetics, Leiden, The Netherlands

Alexander R. Ball Jr.

Affiliation Department of Biological Chemistry, School of Medicine, University of California, Irvine, California, United States of America

Leslie F. Lock

Affiliation Department of Biological Chemistry, School of Medicine, University of California, Irvine, California, United States of America

Peter J. Donovan

Affiliation Department of Biological Chemistry, School of Medicine, University of California, Irvine, California, United States of America

Silvère M. van der Maarel

Affiliation Leiden University Medical Center, Center for Human and Clinical Genetics, Leiden, The Netherlands

Kyoko Yokomori

kyokomor@uci.edu

Affiliation Department of Biological Chemistry, School of Medicine, University of California, Irvine, California, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: WZ HCG KY. Performed the experiments: WZ JCdG YYC RC XK HCG ARB. Analyzed the data: WZ JCdG YYC RC XK HCG STW ARB SMvdM KY. Contributed reagents/materials/analysis tools: XK STW AP KR JAS VEK JB RRF ARB LFL PJD SMvdM. Wrote the paper: WZ STW RRF ARB SMvdM KY. Provided technical support for Alex Ball: LFL.