About the Authors

Björn Schumacher

Affiliation Department of Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands

Ingrid van der Pluijm

Affiliation Department of Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands

Michael J. Moorhouse

Affiliation Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands

Theodore Kosteas

Affiliation Institute of Molecular Biology and Biotechnology, FORTH, Heraklion, Crete, Greece

Andria Rasile Robinson

Affiliation University of Pittsburgh Cancer Institute, Department of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

Yousin Suh

Affiliations Department of Molecular Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America, Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America

Timo M. Breit

Affiliation Integrative Bioinformatics Unit, Institute for Informatics, Faculty of Science, University of Amsterdam, Amsterdam, The Netherlands

Harry van Steeg

Affiliation National Institute of Public Health and the Environment (RIVM), Laboratory of Toxicology, Pathology, and Genetics (TOX), Bilthoven, The Netherlands

Laura J. Niedernhofer

Affiliation University of Pittsburgh Cancer Institute, Department of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

Wilfred van IJcken

Affiliation Erasmus Center for Biomics, Erasmus University Medical Center, Rotterdam, The Netherlands

Andrzej Bartke

Affiliation Department of Internal Medicine, Geriatrics Research, School of Medicine, Southern Illinois University, Springfield, Illinois, United States of America

Stephen R. Spindler

Affiliation Department of Biochemistry, University of California Riverside, Riverside, California, United States of America

Jan H. J. Hoeijmakers

Affiliation Department of Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands

Gijsbertus T. J. van der Horst

g.vanderhorst@erasmusmc.nl (GTJvdH); g.garinis@erasmusmc.nl (GAG)

Affiliation Department of Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands

George A. Garinis

g.vanderhorst@erasmusmc.nl (GTJvdH); g.garinis@erasmusmc.nl (GAG)

Affiliations Department of Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands, Institute of Molecular Biology and Biotechnology, FORTH, Heraklion, Crete, Greece

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: GAG. Performed the experiments: BS MM TK. Analyzed the data: BS MM GAG. Contributed reagents/materials/analysis tools: IvdP ARR YS TB HvS LJN WvI AB SS GvdH. Wrote the paper: BS JHJH GAG.