Expression Profiles Reveal Parallel Evolution of Epistatic Interactions Involving the CRP Regulon in Escherichia coli

Tim F Cooper; Susanna K Remold; Richard E Lenski; Dominique Schneider

doi:10.1371/journal.pgen.0040035

Loading metrics

Open Access

Peer-reviewed

Research Article

Expression Profiles Reveal Parallel Evolution of Epistatic Interactions Involving the CRP Regulon in Escherichia coli

Tim F Cooper ,

*To whom correspondence should be addressed. E-mail: tcooper@central.uh.edu

Affiliation Department of Biology and Biochemistry, University of Houston, Houston, Texas, United States of America
⨯
Susanna K Remold,

Affiliation Department of Biology, University of Louisville, Louisville, Kentucky, United States of America
⨯
Richard E Lenski,

Affiliation Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, United States of America
⨯
Dominique Schneider

Affiliations Laboratoire Adaptation et Pathogénie des Micro-organismes, Université Joseph Fourier Grenoble 1, Grenoble, France , CNRS UMR 5163, Grenoble, France
⨯

Expression Profiles Reveal Parallel Evolution of Epistatic Interactions Involving the CRP Regulon in Escherichia coli

Tim F Cooper,
Susanna K Remold,
Richard E Lenski,
Dominique Schneider

Published: February 15, 2008
https://doi.org/10.1371/journal.pgen.0040035

About the Authors

Tim F Cooper

*To whom correspondence should be addressed. E-mail: tcooper@central.uh.edu

Affiliation Department of Biology and Biochemistry, University of Houston, Houston, Texas, United States of America

Susanna K Remold

Affiliation Department of Biology, University of Louisville, Louisville, Kentucky, United States of America

Richard E Lenski

Affiliation Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, United States of America

Dominique Schneider

Affiliations Laboratoire Adaptation et Pathogénie des Micro-organismes, Université Joseph Fourier Grenoble 1, Grenoble, France , CNRS UMR 5163, Grenoble, France

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

TFC, SKR, REL, and DS conceived and designed the experiments and wrote the paper. TFC and DS performed the experiments. TFC, SKR, and REL analyzed the data. DS contributed reagents/materials/analysis tools.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Regulons
Is the Subject Area "Regulons" applicable to this article?

Thanks for your feedback.
Gene regulation
Is the Subject Area "Gene regulation" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Fitness epistasis
Is the Subject Area "Fitness epistasis" applicable to this article?

Thanks for your feedback.
Evolutionary genetics
Is the Subject Area "Evolutionary genetics" applicable to this article?

Thanks for your feedback.
Point mutation
Is the Subject Area "Point mutation" applicable to this article?

Thanks for your feedback.
Deletion mutation
Is the Subject Area "Deletion mutation" applicable to this article?

Thanks for your feedback.
Epistasis
Is the Subject Area "Epistasis" applicable to this article?

Thanks for your feedback.