About the Authors
- Aron M Geurts
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Affiliations Department of Genetics, Cell Biology, and Development, University of Minnesota Twin Cities, Minneapolis, Minnesota, United States of America , The Arnold and Mabel Beckman Center for Transposon Research, University of Minnesota Twin Cities, Minneapolis, Minnesota, United States of America
- Lara S Collier
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Affiliations The Arnold and Mabel Beckman Center for Transposon Research, University of Minnesota Twin Cities, Minneapolis, Minnesota, United States of America , Cancer Center, University of Minnesota Twin Cities, Minneapolis, Minnesota, United States of America
- Jennifer L Geurts
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Affiliations The Arnold and Mabel Beckman Center for Transposon Research, University of Minnesota Twin Cities, Minneapolis, Minnesota, United States of America , Cancer Center, University of Minnesota Twin Cities, Minneapolis, Minnesota, United States of America
- Leann L Oseth
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Affiliation Institute of Human Genetics, University of Minnesota Twin Cities, Minneapolis, Minnesota, United States of America
- Matthew L Bell
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Affiliation Department of Integrative Physiology, University of Colorado, Boulder, Colorado, United States of America
- David Mu
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Affiliation Genome Research Center, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America
- Robert Lucito
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Affiliation Genome Research Center, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America
- Susan A Godbout
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Affiliation Department of Genetics, Cell Biology, and Development, University of Minnesota Twin Cities, Minneapolis, Minnesota, United States of America
- Laura E Green
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Affiliation The Arnold and Mabel Beckman Center for Transposon Research, University of Minnesota Twin Cities, Minneapolis, Minnesota, United States of America
- Scott W Lowe
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Affiliation Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America
- Betsy A Hirsch
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Affiliations Cancer Center, University of Minnesota Twin Cities, Minneapolis, Minnesota, United States of America , Institute of Human Genetics, University of Minnesota Twin Cities, Minneapolis, Minnesota, United States of America , Laboratory Medicine and Pathology, University of Minnesota Twin Cities, Minneapolis, Minnesota, United States of America
- Leslie A Leinwand
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Affiliation Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, Colorado, United States of America
- David A Largaespada
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*To whom correspondence should be addressed. E-mail: larga002@umn.edu
Affiliations Department of Genetics, Cell Biology, and Development, University of Minnesota Twin Cities, Minneapolis, Minnesota, United States of America , The Arnold and Mabel Beckman Center for Transposon Research, University of Minnesota Twin Cities, Minneapolis, Minnesota, United States of America , Cancer Center, University of Minnesota Twin Cities, Minneapolis, Minnesota, United States of America
Competing Interests
DAL is a founding partner in Discovery Genomics, Inc. (DGI), a biotechnology company pursuing the use of SB and other transposable elements for gene therapy. None of the work described involved DGI.
Author Contributions
AMG, LSC, JLG, LLO, and DAL conceived and designed the experiments. AMG, LSC, JLG, LLO, MLB, DM, RL, SAG, and LEG performed the experiments. AMG, LSC, DM, and RL analyzed the data. AMG, SWL, BAH, and LAL contributed reagents/materials/analysis tools. AMG, LSC, and DAL wrote the paper.