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Disease-Associated Mutations Disrupt Functionally Important Regions of Intrinsic Protein Disorder

  • Vladimir Vacic,

    Affiliation Department of Computer Science, Columbia University, New York, New York, United States of America

  • Phineus R. L. Markwick,

    Affiliations Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, California, United States of America, Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America

  • Christopher J. Oldfield,

    Affiliation Center for Computational Biology and Bioinformatics, Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

  • Xiaoyue Zhao,

    Current address: Google Inc, Mountain View, California, United States of America

    Affiliation Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America

  • Chad Haynes,

    Current address: WaterSmart Software, San Francisco, California, United States of America

    Affiliation Laboratory of Statistical Genetics, The Rockefeller University, New York, New York, United States of America

  • Vladimir N. Uversky,

    Affiliations Department of Molecular Medicine, University of South Florida College of Medicine, Tampa, Florida, United States of America, Institute for Biological Instrumentation, Russian Academy of Sciences, Pushchino, Moscow Region, Russia

  • Lilia M. Iakoucheva

    lilyak@ucsd.edu

    Affiliation Department of Psychiatry, University of California San Diego, La Jolla, California, United States of America

Disease-Associated Mutations Disrupt Functionally Important Regions of Intrinsic Protein Disorder

  • Vladimir Vacic, 
  • Phineus R. L. Markwick, 
  • Christopher J. Oldfield, 
  • Xiaoyue Zhao, 
  • Chad Haynes, 
  • Vladimir N. Uversky, 
  • Lilia M. Iakoucheva
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