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Differential temperature sensitivity of synaptic and firing processes in a neural mass model of epileptic discharges explains heterogeneous response of experimental epilepsy to focal brain cooling

Fig 4

Response functions and the effect of Q10.

Different populations of neurons have different post-synaptic impulse response (solid lines, left) but are assumed to have the same firing response (solid line, right). Q10,syn scales down the post-synaptic impulse response curves (broken lines, left) while Q10,int changes the properties of the firing response curve (broken line, right).

Fig 4

doi: https://doi.org/10.1371/journal.pcbi.1005736.g004