In silico assessment of genetic variation in KCNA5 reveals multiple mechanisms of human atrial arrhythmogenesis
A Steady-state activation and inactivation; B Time constants; C Current trace obtained from a simulated voltage clamp. Inserts: top right–voltage protocol; bottom right–experimental current traces; D I-V relationship. In the Fig the simulation data were shown using lines, and experimental data represented by points. Experimental data were taken from ; specially, for B the time constants were derived from current traces from  by fitting the activation phase of the current trace to a mono-exponential equation.