Computational Analysis of Residue Interaction Networks and Coevolutionary Relationships in the Hsp70 Chaperones: A Community-Hopping Model of Allosteric Regulation and Communication
Fig 5
Structural Mapping of Coevolving Residues in the DnaK Forms.
Structural mapping of high pMI residues (top 5%) onto ADP-DnaK (A) and ATP-DnaK forms (B). Mapping of high cMI residues (top 5%) onto ADP-DnaK and ATP-DnaK is shown on panels (C) and (D) respectively. The top 5% of high pMI residues (A, B) and high cMI residues (C, D) are in spheres (only Cα atoms are shown).