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A General Shear-Dependent Model for Thrombus Formation

Fig 8

Simulation results for platelet aggregation at high shear rates in a fixed geometry with 60% stenosis, whereas the increase in flow rate develops high shear rates in the stenosis.

Printed number in each figure is the undisturbed maximum wall shear rates encountered in each stenosis (before aggregation occurs). Full occlusion is observed in (b) and (c). Color coding for particles is the same as in Fig 3, and green particles are seeded on the circular arc only. Here, the activation delay time is τact = 0 s. (d) and (h) Wall shear rate contours plotted on the opposite wall of the arc for the simulations with undisturbed wall shear rate values of 15,000 and 28,000 s−1, respectively.

Fig 8

doi: https://doi.org/10.1371/journal.pcbi.1005291.g008