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PhyloBot: A Web Portal for Automated Phylogenetics, Ancestral Sequence Reconstruction, and Exploration of Mutational Trajectories

Fig 1

Summary of PhyloBot automated pipeline.

A user begins by uploading a collection of orthologous protein sequences in a FASTA-formatted text file. PhyloBot reads the sequence collection and launches its automated analysis pipeline, which includes sequence alignment, phylogenetic model-fitting, tests of branch support, ancestral sequence reconstruction, and prediction of functional genetics. Upon completion, the results can be viewed in a web browser.

Fig 1